HAMAP rule MF_02033
General rule information
[?]
| PURL | https://purl.expasy.org/hamap/rule/MF_02033 |
| Accession | MF_02033 |
| Dates | 05-JUN-2015 (Created)
01-JUN-2023 (Last updated, Version 6) |
| Name | FtsA |
| Scope(s) |
Bacteria |
| Template(s) | P0ABH0; P28264; [ Recover all ] |
| Triggered by |
HAMAP; MF_02033 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier | FTSA |
| Protein name | RecName: Full=Cell division protein FtsA; |
| Gene name | Name=ftsA; |
Comments
[?]
| FUNCTION | Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. |
| SUBUNIT | Self-interacts. Interacts with FtsZ. |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix. |
| else | |
| SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix. |
| end case | |
| SIMILARITY | Belongs to the FtsA/MreB family. |
Keywords
[?]
| Cell cycle | |
| Cell division | |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Cell membrane | |
| Membrane | |
Gene Ontology
[?]
| GO:0043093; Biological process:FtsZ-dependent cytokinesis |
| GO:0032153; Cellular component:cell division site |
| GO:0009898; Cellular component:cytoplasmic side of plasma membrane |
Cross-references
[?]
| Pfam | PF02491; SHS2_FTSA; 1; |
| NCBIfam | TIGR01174; ftsA; 1; |
| PIRSF | PIRSF003101; FtsA; 1; |
Features
[?]
Additional information
[?]
| Size range | 350-540 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | FtsA may play a more critical role in Z ring assembly in organisms that don't have a ZipA homolog (PubMed:16159787). |