HAMAP rule MF_02033

General rule information [?]

Accession	MF_02033
Dates	5-JUN-2015 (Created) 1-JUN-2023 (Last updated, Version 5)
Name	FtsA
Scope(s)	Bacteria
Template(s)	P0ABH0 (FTSA_ECOLI); P28264 (FTSA_BACSU); [ Recover all ]
Triggered by	HAMAP; MF_02033 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	FTSA
Protein name	RecName: Full=Cell division protein FtsA;
Gene name	Name=ftsA;

Comments [?]

FUNCTION	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
SUBUNIT	Self-interacts. Interacts with FtsZ.
case defined <Property:Membrane> and <Property:Membrane=2>
SUBCELLULAR LOCATION	Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
else
SUBCELLULAR LOCATION	Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
end case
SIMILARITY	Belongs to the FtsA/MreB family.

Keywords [?]

Cell cycle
Cell division
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Membrane

Gene Ontology [?]

GO:0043093; Biological process:FtsZ-dependent cytokinesis

GO:0032153; Cellular component:cell division site

GO:0009898; Cellular component:cytoplasmic side of plasma membrane

Cross-references [?]

Features [?]

Additional information [?]

Size range	350-540 amino acids
Related rules	None
Fusion	Nter: None Cter: None
Comments	FtsA may play a more critical role in Z ring assembly in organisms that don't have a ZipA homolog (PubMed:16159787).