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HAMAP rule MF_02046

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General rule information [?]

Accession MF_02046
Dates 27-AUG-2015 (Created)
19-NOV-2022 (Last updated, Version 5)
Name Glc6PDH_archaea
Template D4GS48 (G6PD_HALVD)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=NAD-dependent glucose-6-phosphate dehydrogenase;

Comments [?]

Function Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
Catalytic activity RHEA:38215: D-glucose 6-phosphate + NAD(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADH
Pathway Carbohydrate degradation; pentose phosphate pathway.
Subunit Homodimer.
Similarity Belongs to the NAD(P)-dependent epimerase/dehydratase family.

Keywords [?]

Gene Ontology [?]

GO:0016616; Molecular function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor.
GO:0051287; Molecular function: NAD binding.
GO:0051156; Biological process: glucose 6-phosphate metabolic process.

Cross-references [?]

Pfam PF01370; Epimerase; 1;

Features [?]

From: G6PD_HALVD (D4GS48)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     152     152       Proton acceptor     Y  
BINDING (Optional)     90     90       /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540     N  
BINDING (Optional)     115     115       /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540     S  
BINDING (Optional)     152     152       /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540     Y  
BINDING (Optional)     156     156       /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540     K  

Additional information [?]

Size range 230-310 amino acids
Related rules None
Fusion None