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Annotation rule MF_02052
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General rule information [?]

Accession MF_02052
Dates 7-JAN-2016 (Created)
5-MAY-2020 (Last updated, Version 5)
Name LsrF
Scope
Bacteria; Enterobacterales
Template P76143 (LSRF_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
LSRF
Protein name
RecName: Full=3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase;
EC 2.3.1.245;
Gene name
lsrF

Comments [?]

Function Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
Catalytic activity RHEA:44736: acetyl-CoA + dihydroxyacetone phosphate = 3-hydroxy-2,4-dioxopentyl phosphate + CoA
EC 2.3.1.245
Subunit Homodecamer.
Subcellular location Cytoplasm.
Similarity Belongs to the DeoC/FbaB aldolase family.

Keywords [?]


Gene Ontology [?]

GO:0016747; Molecular function: transferase activity, transferring acyl groups other than amino-acyl groups.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01791; DeoC; 1;
PIRSF PIRSF038992; Aldolase_Ia; 1;

Features [?]

From: LSRF_ECOLI (P76143)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     203     203       Schiff-base intermediate with substrate     K  

Additional information [?]

Size range 290-310 amino acids
Related rules None
Fusion None