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Annotation rule MF_02056 |
Accession | MF_02056 |
Dates | 15-FEB-2016 (Created) 20-NOV-2019 (Last updated, Version 3) |
Name | MetZ |
Scope | Bacteria |
Templates | P55218 (METZ_PSEAE); P9WGB5 (METZ_MYCTU): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide. |
Catalytic activity | RHEA:27826: hydrogen sulfide + O-succinyl-L-homoserine = L-homocysteine + succinate |
Cofactor | pyridoxal 5'-phosphate |
Pathway | Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homocysteine from O-succinyl-L-homoserine: step 1/1. |
Subunit | Homotetramer. |
Similarity | Belongs to the trans-sulfuration enzymes family. MetZ subfamily. |
PROSITE | PS00868; CYS_MET_METAB_PP; 1; |
Pfam | PF01053; Cys_Met_Meta_PP; 1; |
TIGRFAMs | TIGR01325; O_suc_HS_sulf; 1; |
PIRSF | PIRSF001434; CGS; 1; |
From: METZ_MYCTU (P9WGB5) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
MOD_RES | 219 | 219 | N6-(pyridoxal phosphate)lysine | K |
Size range | 380-460 amino acids |
Related rules | None |
Fusion | None |