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Annotation rule MF_02057
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General rule information [?]

Accession MF_02057
Dates 8-MAR-2016 (Created)
20-NOV-2019 (Last updated, Version 4)
Name tRNA_methyltr_CmoM
Scope
Bacteria; Gammaproteobacteria
Templates P36566 (CMOM_ECOLI); Q8XDG3 (CMOM_ECO57): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CMOM
Protein name
RecName: Full=tRNA 5-carboxymethoxyuridine methyltransferase;
EC 2.1.1.-;
AltName: Full=cmo5U methyltransferase;
Gene name
cmoM

Comments [?]

Function Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
Catalytic activity RHEA:54080: 5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-methionine = 5-methoxycarbonylmethoxyuridine(34) in tRNA + S-adenosyl-L-homocysteine
Similarity Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.

Keywords [?]

Methyltransferase
S-adenosyl-L-methionine
Transferase
tRNA processing

Gene Ontology [?]

GO:0097697; Molecular function: tRNA 5-carboxymethoxyuridine methyltransferase activity.
GO:0006400; Biological process: tRNA modification.

Cross-references [?]

Pfam PF13847; Methyltransf_31; 0-1;
PF08241; Methyltransf_11; 0-1;

Features [?]

From: CMOM_ECO57 (Q8XDG3)
Key     From     To       Description   Tag   Condition   FTGroup
REGION (Optional)     52     53       S-adenosyl-L-methionine binding     G-[GA]  
REGION (Optional)     102     103       S-adenosyl-L-methionine binding     A-Q  
BINDING (Optional)     26     26       S-adenosyl-L-methionine     R  
BINDING (Optional)     73     73       S-adenosyl-L-methionine     [DE]  
BINDING (Optional)     119     119       S-adenosyl-L-methionine; via carbonyl oxygen     H  

Additional information [?]

Size range 240-320 amino acids
Related rules None
Fusion None


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