HAMAP rule MF_02057

General rule information [?]

Accession	MF_02057
Dates	8-MAR-2016 (Created) 13-OCT-2023 (Last updated, Version 8)
Name	tRNA_methyltr_CmoM
Scope(s)	Bacteria Gammaproteobacteria
Template(s)	P36566 (CMOM_ECOLI); Q8XDG3 (CMOM_ECO57); [ Recover all ]
Triggered by	HAMAP; MF_02057 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	CMOM
Protein name	RecName: Full=tRNA 5-carboxymethoxyuridine methyltransferase; EC=2.1.1.-; AltName: Full=cmo5U methyltransferase;
Gene name	Name=cmoM;

Comments [?]

FUNCTION	Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
CATALYTIC ACTIVITY	Reaction=5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-methionine = 5-methoxycarbonylmethoxyuridine(34) in tRNA + S-adenosyl-L- homocysteine; Xref=Rhea:RHEA:54080, Rhea:RHEA-COMP:13383, Rhea:RHEA- COMP:13781, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:136879, ChEBI:CHEBI:138053;
SIMILARITY	Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.

Keywords [?]

Gene Ontology [?]

GO:0097697; Molecular function:tRNA (5-carboxymethoxyuridine(34)-5-O)-methyltransferase activity

GO:0006400; Biological process:tRNA modification

Cross-references [?]

Pfam	PF13847; Methyltransf_31; 0-1;
Pfam	PF08241; Methyltransf_11; 0-1;

Features [?]

From: CMOM_ECO57 (Q8XDG3)

Key

From

Description

Tag

Condition

FTGroup

BINDING