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| Annotation rule MF_02061 |
General rule information
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| Accession | MF_02061 |
| Dates | 30-MAR-2016 (Created) 4-APR-2020 (Last updated, Version 6) |
| Name | Thiored_glutath_peroxid |
| Scope | Bacteria; Enterobacterales |
| Template | P06610 (BTUE_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. |
| Catalytic activity | RHEA:16833: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O
EC 1.11.1.9 |
| RHEA:62620: [thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O
EC 1.11.1.24 |
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| Similarity | Belongs to the glutathione peroxidase family. BtuE subfamily. |
Keywords
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Gene Ontology
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GO:0004602; Molecular function: glutathione peroxidase activity.
GO:0051920; Molecular function: peroxiredoxin activity.
GO:0051920; Molecular function: peroxiredoxin activity.
Cross-references
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| PROSITE | PS00460; GLUTATHIONE_PEROXID_1; 1; |
| PS00763; GLUTATHIONE_PEROXID_2; 1; | |
| PS51355; GLUTATHIONE_PEROXID_3; 1; | |
| Pfam | PF00255; GSHPx; 1; |
| PRINTS | PR01011; GLUTPROXDASE; 1; |
| PIRSF | PIRSF000303; Glutathion_perox; 1; |
Features
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| From: BTUE_ECOLI (P06610) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 37 | 37 | C | |||||||||
Additional information
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| Size range | 180-200 amino acids |
| Related rules | None |
| Fusion | None |