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HAMAP rule MF_02068

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General rule information [?]

Accession MF_02068
Dates 12-JUL-2016 (Created)
19-NOV-2022 (Last updated, Version 6)
Name TarI
Scope(s) Bacteria
Template(s) Q8DPI2 (TARI_STRR6); Q8RKI9 (TARI_BACSH); Q2G1C0 (TARI1_STAA8); Q2G2C4 (TARI2_STAA8); [ Recover all ]
Triggered by HAMAP; MF_02068 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TARI
Protein name RecName: Full=Ribitol-5-phosphate cytidylyltransferase;
case <OC:Bacilli>
Gene name Name=tarI;
end case

Comments [?]

FUNCTIONCatalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate.
CATALYTIC ACTIVITY Reaction=CTP + D-ribitol 5-phosphate + H(+) = CDP-L-ribitol + diphosphate; Xref=Rhea:RHEA:12456, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:37563, ChEBI:CHEBI:57608, ChEBI:CHEBI:57695; EC=;
case <OC:Bacilli>
PATHWAYCell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis.
end case
SIMILARITYBelongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.

Keywords [?]

Gene Ontology [?]

GO:0047349; Molecular function:D-ribitol-5-phosphate cytidylyltransferase activity
case <OCellular component:Bacilli>
GO:1902012; Biological process:poly(ribitol phosphate) teichoic acid biosynthetic process
end case

Cross-references [?]

Pfam PF01128; IspD; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 7 10 /ligand="CTP"
BINDING 82 88 /ligand="CTP"
BINDING 113 113 /ligand="CTP"
SITE 14 14 /note="Transition state stabilizer" R
SITE 22 22 /note="Transition state stabilizer" K
SITE 161 161 /note="Positions ribitol 5-phosphate for the nucleophilic attack" R
SITE 218 218 /note="Positions ribitol 5-phosphate for the nucleophilic attack" K

Additional information [?]

Size range 220-260 amino acids
Related rules None
Fusion Nter: None Cter: None

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