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HAMAP rule MF_02068

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General rule information [?]

Accession MF_02068
Dates 12-JUL-2016 (Created)
19-NOV-2022 (Last updated, Version 6)
Name TarI
Scope
Bacteria
Templates Q8DPI2 (TARI_STRR6); Q8RKI9 (TARI_BACSH); Q2G1C0 (TARI1_STAA8); Q2G2C4 (TARI2_STAA8): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TARI
Protein name
RecName: Full=Ribitol-5-phosphate cytidylyltransferase;
EC 2.7.7.40;
case <OC:Bacilli>
Gene name
tarI
end case

Comments [?]

Function Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
Catalytic activity RHEA:12456: CTP + D-ribitol 5-phosphate + H(+) = CDP-L-ribitol + diphosphate
EC 2.7.7.40
case <OC:Bacilli>
Pathway Cell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis.
end case
Similarity Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.

Keywords [?]

case <OC:Bacilli>
end case

Gene Ontology [?]

GO:0047349; Molecular function: D-ribitol-5-phosphate cytidylyltransferase activity.
case <OC:Bacilli>
GO:1902012; Biological process: poly(ribitol phosphate) teichoic acid biosynthetic process.
end case

Cross-references [?]

PROSITE PS01295; ISPD; 1;
Pfam PF01128; IspD; 1;

Features [?]

From: TARI_STRR6 (Q8DPI2)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING (Optional)     7     10       /ligand="CTP" /ligand_id="ChEBI:CHEBI:37563     [LF]-A-G-G  
BINDING (Optional)     82     88       /ligand="CTP" /ligand_id="ChEBI:CHEBI:37563     G-x(3)-[NQ]-x-[ST]  
BINDING (Optional)     113     113       /ligand="CTP" /ligand_id="ChEBI:CHEBI:37563     S  
SITE     14     14       Transition state stabilizer     R  
SITE     22     22       Transition state stabilizer     K  
SITE     161     161       Positions ribitol 5-phosphate for the nucleophilic attack     R  
SITE     218     218       Positions ribitol 5-phosphate for the nucleophilic attack     K  

Additional information [?]

Size range 220-260 amino acids
Related rules None
Fusion None