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HAMAP rule MF_02069

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General rule information [?]

Accession MF_02069
Dates 14-JUL-2016 (Created)
19-NOV-2022 (Last updated, Version 6)
Name TarJ
Scope(s) Bacteria
Template(s) Q8DPI3 (TARJ_STRR6); Q8RKJ0 (TARJ_BACSH); Q2G1B9 (TARJ1_STAA8); Q2G1C4 (TARJ2_STAA8); [ Recover all ]
Triggered by HAMAP; MF_02069 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TARJ
Protein name RecName: Full=Ribulose-5-phosphate reductase;
                 Short=Ribulose-5-P reductase;
AltName: Full=Ribitol-5-phosphate dehydrogenase;
case <OC:Bacilli>
Gene name Name=tarJ;
end case

Comments [?]

FUNCTIONCatalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate.
CATALYTIC ACTIVITY Reaction=D-ribitol 5-phosphate + NADP(+) = D-ribulose 5-phosphate + H(+) + NADPH; Xref=Rhea:RHEA:19921, ChEBI:CHEBI:15378, ChEBI:CHEBI:57695, ChEBI:CHEBI:57783, ChEBI:CHEBI:58121, ChEBI:CHEBI:58349; EC=;
COFACTOR Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
case <OC:Bacilli>
PATHWAYCell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis.
end case
SIMILARITYBelongs to the zinc-containing alcohol dehydrogenase family.

Keywords [?]

Gene Ontology [?]

GO:0050256; Molecular function:ribitol-5-phosphate 2-dehydrogenase activity
GO:0008270; Molecular function:zinc ion binding
case <OCellular component:Bacilli>
GO:1902012; Biological process:poly(ribitol phosphate) teichoic acid biosynthetic process
end case

Cross-references [?]

Pfam PF08240; ADH_N; 1;
Pfam PF00107; ADH_zinc_N; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 45 45 /ligand="Zn(2+)"
C 1
BINDING 71 71 /ligand="Zn(2+)"
H 1
BINDING 72 72 /ligand="Zn(2+)"
E 1
BINDING 151 151 /ligand="Zn(2+)"
E 1

Additional information [?]

Size range 330-370 amino acids
Related rules None
Fusion Nter: None Cter: None

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