HAMAP rule MF_02069

General rule information [?]

Accession	MF_02069
Dates	14-JUL-2016 (Created) 19-NOV-2022 (Last updated, Version 6)
Name	TarJ
Scope(s)	Bacteria
Template(s)	Q8DPI3 (TARJ_STRR6); Q8RKJ0 (TARJ_BACSH); Q2G1B9 (TARJ1_STAA8); Q2G1C4 (TARJ2_STAA8); [ Recover all ]
Triggered by	HAMAP; MF_02069 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	TARJ
Protein name	RecName: Full=Ribulose-5-phosphate reductase; Short=Ribulose-5-P reductase; EC=1.1.1.405; AltName: Full=Ribitol-5-phosphate dehydrogenase;
case <OC:Bacilli>
Gene name	Name=tarJ;
end case

Comments [?]

FUNCTION	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate.
CATALYTIC ACTIVITY	Reaction=D-ribitol 5-phosphate + NADP(+) = D-ribulose 5-phosphate + H(+) + NADPH; Xref=Rhea:RHEA:19921, ChEBI:CHEBI:15378, ChEBI:CHEBI:57695, ChEBI:CHEBI:57783, ChEBI:CHEBI:58121, ChEBI:CHEBI:58349; EC=1.1.1.405;
COFACTOR	Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
case <OC:Bacilli>
PATHWAY	Cell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis.
end case
SIMILARITY	Belongs to the zinc-containing alcohol dehydrogenase family.

Keywords [?]

Metal-binding
NADP
Oxidoreductase
Zinc
case <OC:Bacilli>
Cell wall biogenesis/degradation
Teichoic acid biosynthesis
end case

Gene Ontology [?]

GO:0050256; Molecular function:ribitol-5-phosphate 2-dehydrogenase activity
GO:0008270; Molecular function:zinc ion binding
case <OCellular component:Bacilli>
GO:1902012; Biological process:poly(ribitol phosphate) teichoic acid biosynthetic process
end case

Cross-references [?]

Features [?]

From: TARJ_STRR6 (Q8DPI3)

Key

From

Description

Tag

Condition

FTGroup

BINDING

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_note="catalytic"

BINDING

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_note="catalytic"

BINDING

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_note="catalytic"

BINDING

151

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_note="catalytic"

Additional information [?]