![]() |
|
Annotation rule MF_02076 |
Accession | MF_02076 |
Dates | 10-NOV-2016 (Created) 20-NOV-2019 (Last updated, Version 4) |
Name | Glu_tRNA_synth_type2 |
Scope | Archaea |
Templates | P04805 (SYE_ECOLI); O25360 (SYE2_HELPY); P27000 (SYE_THET8); Q8DLI5 (SYE_THEEB): [Recover all] |
Triggered by |
Identifier |
|
Protein name |
|
Gene name |
|
Function | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). |
Catalytic activity | RHEA:23540: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)
EC 6.1.1.17 |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily. |
PROSITE | PS00178; AA_TRNA_LIGASE_I; 1; |
Pfam | PF00749; tRNA-synt_1c; 1; |
PF03950; tRNA-synt_1c_C; 1; | |
PRINTS | PR00987; TRNASYNTHGLU; 1; |
TIGRFAMs | TIGR00463; gltX_arch; 1; |
From: SYE_METJA (Q58772) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
MOTIF | 98 | 108 | 'HIGH' region | P-[SNE]-P-x(4)-[HTS]-[LIVM]-G-x |
Size range | 530-640 amino acids |
Related rules | MF_01428 (GLUQ) |
Fusion | None |
Comments | This signature is specific for archaeal and eukaryotic cytoplasmic glutamate--tRNA ligases. See MF_00022 for bacterial and eukaryotic mitochondrial glutamate--tRNA ligases. |