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Annotation rule MF_02089
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General rule information [?]

Accession MF_02089
Dates 23-MAR-2017 (Created)
20-NOV-2019 (Last updated, Version 3)
Name QueH
Scope
Bacteria
Templates A0A0H3JUG6 (QUEH_STAAM); Q7VYQ1 (QUEH_BORPE); Q3Z8V0 (QUEH_DEHM1); Q0I1Q0 (QUEH_HAES1); A0A0H2VKG8 (QUEH_STAES); Q9A1K3 (QUEH_STRP1); Q9WZJ0 (QUEH_THEMA); O24926 (QUEH_HELPY): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
QUEH
Protein name
RecName: Full=Epoxyqueuosine reductase QueH;
EC 1.17.99.6;
AltName: Full=Queuosine biosynthesis protein QueH;
Gene name
queH

Comments [?]

Function Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
Catalytic activity RHEA:32159: AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA
EC 1.17.99.6
Pathway tRNA modification; tRNA-queuosine biosynthesis.
Similarity Belongs to the QueH family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

GO:0052693; Molecular function: epoxyqueuosine reductase activity.
case <FTGroup:1>
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding.
end case
GO:0008616; Biological process: queuosine biosynthetic process.
GO:0008033; Biological process: tRNA processing.

Cross-references [?]

Pfam PF02677; DUF208; 1;

Features [?]

From: QUEH_STAAM (A0A0H3JUG6)
Key     From     To       Description   Tag   Condition   FTGroup
METAL     43     43       Iron-sulfur (4Fe-4S)     C   1
METAL     44     44       Iron-sulfur (4Fe-4S)     C   1
METAL     129     129       Iron-sulfur (4Fe-4S)     C   1
METAL     132     132       Iron-sulfur (4Fe-4S)     C   1
DISULFID     211     213       Redox-active     C-x*-C  

Additional information [?]

Size range 170-370 amino acids
Related rules None
Fusion None
Comments Longer C-terminal domain in some species.