HAMAP rule MF_02089
General rule information
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Accession | MF_02089 |
Dates | 23-MAR-2017 (Created) 9-MAR-2023 (Last updated, Version 6) |
Name | QueH |
Scope | Bacteria |
Templates | A0A0H3JUG6 (QUEH_STAAM); Q7VYQ1 (QUEH_BORPE); Q3Z8V0 (QUEH_DEHM1); Q0I1Q0 (QUEH_HISS1); A0A0H2VKG8 (QUEH_STAES); Q9A1K3 (QUEH_STRP1); Q9WZJ0 (QUEH_THEMA); O24926 (QUEH_HELPY): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). |
Catalytic activity | RHEA:32159: AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA
EC 1.17.99.6 |
Pathway | tRNA modification; tRNA-queuosine biosynthesis. |
Similarity | Belongs to the QueH family. |
Keywords
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case <FTGroup:1>
end case
Gene Ontology
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GO:0052693; Molecular function: epoxyqueuosine reductase activity.
case <FTGroup:1>
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding.
end case
GO:0008616; Biological process: queuosine biosynthetic process.
GO:0008033; Biological process: tRNA processing.
GO:0008033; Biological process: tRNA processing.
Cross-references
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Pfam | PF02677; DUF208; 1; |
Features
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From: QUEH_STAAM (A0A0H3JUG6) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 43 | 43 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | 1 | |||||||
BINDING | 44 | 44 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | 1 | |||||||
BINDING | 129 | 129 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | 1 | |||||||
BINDING | 132 | 132 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | 1 | |||||||
DISULFID | 211 | 213 | Redox-active | C-x*-C |
Additional information
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Size range | 170-370 amino acids |
Related rules | None |
Fusion | None |
Comments | Longer C-terminal domain in some species. |