HAMAP rule MF_02092

General rule information [?]

Accession	MF_02092
Dates	12-JUL-2017 (Created) 26-JAN-2023 (Last updated, Version 6)
Name	DLDH_Dld
Scope(s)	Bacteria
Template(s)	P06149 (DLD_ECOLI); Q8NRY8 (DLD_CORGL); [ Recover all ]
Triggered by	HAMAP; MF_02092 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	DLD
Protein name	RecName: Full=Quinone-dependent D-lactate dehydrogenase; EC=1.1.5.12; AltName: Full=D-lactate dehydrogenase; Short=D-LDH;
Gene name	Name=dld;

Comments [?]

FUNCTION	Catalyzes the oxidation of D-lactate to pyruvate.
CATALYTIC ACTIVITY	Reaction=(R)-lactate + a quinone = a quinol + pyruvate; Xref=Rhea:RHEA:51468, ChEBI:CHEBI:15361, ChEBI:CHEBI:16004, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.12;
COFACTOR	Name=FAD; Xref=ChEBI:CHEBI:57692;
case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
SUBCELLULAR LOCATION	Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
else
SUBCELLULAR LOCATION	Cell membrane; Peripheral membrane protein; Cytoplasmic side.
end case
SIMILARITY	Belongs to the quinone-dependent D-lactate dehydrogenase family.

Keywords [?]

case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
Cell inner membrane
end case
Cell membrane
FAD
Flavoprotein
Membrane
Oxidoreductase
Quinone

Gene Ontology [?]

GO:0016901; Molecular function:oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor

GO:0050660; Molecular function:flavin adenine dinucleotide binding

GO:0019516; Biological process:lactate oxidation

GO:0031234; Cellular component:extrinsic component of cytoplasmic side of plasma membrane

Cross-references [?]

Features [?]

From: DLD_ECOLI (P06149)

Key

From

Description

Tag

Condition

FTGroup

BINDING