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HAMAP rule MF_02093

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General rule information [?]

Accession MF_02093
Dates 29-AUG-2017 (Created)
1-JUN-2023 (Last updated, Version 8)
Name Beta_carotene_diox
Scope(s) Bacteria
Template(s) Q4PNI0 (BLH_UNCMB); [ Recover all ]
Triggered by HAMAP; MF_02093 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier BLH
Protein name RecName: Full=Probable beta-carotene 15,15'-dioxygenase;

Comments [?]

FUNCTIONCatalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
CATALYTIC ACTIVITY Reaction=all-trans-beta-carotene + O2 = 2 all-trans-retinal; Xref=Rhea:RHEA:32887, ChEBI:CHEBI:15379, ChEBI:CHEBI:17579, ChEBI:CHEBI:17898; EC=;
COFACTOR Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
SIMILARITYBelongs to the Brp/Blh beta-carotene diooxygenase family.

Keywords [?]

Gene Ontology [?]

GO:0005506; Molecular function:iron ion binding
GO:0010436; Molecular function:carotenoid dioxygenase activity
GO:0016121; Biological process:carotene catabolic process
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF15461; BCD; 1;
NCBIfam TIGR03753; blh_monoox; 1;
General Transmembrane; -; 7-10;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 21 21 /ligand="Fe cation"
H 1
BINDING 78 78 /ligand="Fe cation"
H 1
BINDING 188 188 /ligand="Fe cation"
H 1
BINDING 192 192 /ligand="Fe cation"
H 1

Additional information [?]

Size range 240-390 amino acids
Related rules None
Fusion Nter: None Cter: None

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