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Annotation rule MF_02095
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General rule information [?]

Accession MF_02095
Dates 13-OCT-2017 (Created)
20-NOV-2019 (Last updated, Version 3)
Name CysQ
Scope
Bacteria
Template P22255 (CYSQ_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CYSQ
Protein name
RecName: Full=3'(2'),5'-bisphosphate nucleotidase CysQ;
EC 3.1.3.7;
AltName: Full=3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase;
AltName: Full=3'-phosphoadenosine 5'-phosphate phosphatase;
Short=PAP phosphatase;
Gene name
cysQ

Comments [?]

Function Converts adenosine-3',5'-bisphosphate (PAP) to AMP.
Catalytic activity RHEA:10040: adenosine 3',5'-bisphosphate + H2O = AMP + phosphate
EC 3.1.3.7
Cofactor Mg(2+)
case <OC:Proteobacteria> or (defined <Property:Membrane> and <Property:Membrane=2>)
Subcellular location Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
else
Subcellular location Cell membrane; Peripheral membrane protein; Cytoplasmic side.
end case
Similarity Belongs to the inositol monophosphatase superfamily. CysQ family.

Keywords [?]

case <OC:Proteobacteria> or (defined <Property:Membrane> and <Property:Membrane=2>)
end case

Gene Ontology [?]

GO:0008441; Molecular function: 3'(2'),5'-bisphosphate nucleotidase activity.
GO:0000287; Molecular function: magnesium ion binding.

Cross-references [?]

PROSITE PS00629; IMP_1; 1;
PS00630; IMP_2; 1;
Pfam PF00459; Inositol_P; 1;
PRINTS PR00377; IMPHPHTASES; 1;
TIGRFAMs TIGR01331; bisphos_cysQ; 1;

Features [?]

From: CYSQ_ECOLI (P22255)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     85     88       Substrate binding     [LIV]-D-G-T  
METAL     64     64       Magnesium 1     E  
METAL     83     83       Magnesium 1     D  
METAL     83     83       Magnesium 2     D  
METAL     85     85       Magnesium 1; via carbonyl oxygen     [LIV]  
METAL     86     86       Magnesium 2     D  
METAL     205     205       Magnesium 2     D  
BINDING     64     64       Substrate     E  
BINDING     205     205       Substrate     D  

Additional information [?]

Size range 220-320 amino acids
Related rules None
Fusion None