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Annotation rule MF_02126 |
Accession | MF_02126 |
Dates | 28-OCT-2011 (Created) 20-NOV-2019 (Last updated, Version 6) |
Name | RF_methyltr_PrmC |
Scope | Bacteria |
Templates | P0ACC1 (PRMC_ECOLI); Q9WYV8 (PRMC_THEMA); B0B9D1 (PRMC_CHLT2): [Recover all] |
Triggered by |
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Protein name |
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Gene name |
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Function | Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. |
Catalytic activity | RHEA:42896: L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine
EC 2.1.1.297 |
Similarity | Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. |
From: PRMC_ECOLI (P0ACC1) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION (Optional) | 117 | 121 | S-adenosyl-L-methionine binding | G-x-G-x-G | ||||||||
REGION | 183 | 186 | Substrate binding | N-P-P-Y | ||||||||
BINDING | 140 | 140 | S-adenosyl-L-methionine | [DE] | ||||||||
BINDING (Optional) | 168 | 168 | S-adenosyl-L-methionine | [WF] | ||||||||
BINDING | 183 | 183 | S-adenosyl-L-methionine | N |
Size range | 270-354 amino acids |
Related rules | None |
Fusion | Nter: None; Cter: MF_01057 (trmB) |