HAMAP rule MF_02203
General rule information
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| Accession | MF_02203 |
| Dates | 1-FEB-2018 (Created)
1-JUN-2023 (Last updated, Version 5) |
| Name | TolR |
| Scope(s) |
Bacteria Pseudomonadota |
| Template(s) | P0ABV6 (TOLR_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_02203 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | TOLR |
| Protein name | RecName: Full=Tol-Pal system protein TolR; |
| Gene name | Name=tolR; |
Comments
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| case <OC:Enterobacterales> | |
| FUNCTION | Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. |
| else | |
| FUNCTION | Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. |
| end case | |
| SUBUNIT | The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
| SIMILARITY | Belongs to the ExbD/TolR family. |
Keywords
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| Cell cycle |
| Cell division |
| Cell inner membrane |
| Cell membrane |
| Membrane |
| Transmembrane |
| Transmembrane helix |
Gene Ontology
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| GO:0051301; Biological process:cell division |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF02472; ExbD; 1; |
| NCBIfam | TIGR02801; tolR; 1; |
| General | Transmembrane; -; 1; |
Features
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Additional information
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| Size range | 125-160 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |