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HAMAP rule MF_02205

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General rule information [?]

Accession MF_02205
Dates 13-FEB-2018 (Created)
26-JAN-2023 (Last updated, Version 8)
Name DinG_proteobact
Scope(s) Bacteria
Pseudomonadota
Template(s) P27296 (DING_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_02205 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DING
RecName: Full=ATP-dependent DNA helicase DinG;<br /> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;EC=<a href="https://enzyme.expasy.org/EC/3.6.4.12">3.6.4.12</a>;
Gene name Name=dinG;

Comments [?]

FUNCTIONDNA-dependent ATPase and 5'-3' DNA helicase.
CATALYTIC ACTIVITY Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
COFACTOR Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Note=Binds 1 [4Fe-4S] cluster
SIMILARITYBelongs to the helicase family. DinG subfamily. Type 1 sub- subfamily.

Keywords [?]

4Fe-4S
ATP-binding
DNA-binding
<a href="https://www.uniprot.org/keywords/KW-0347">Helicase</a>
Hydrolase
Iron
Iron-sulfur
Metal-binding
Nucleotide-binding

Gene Ontology [?]

GO:0003678; Molecular function:DNA helicase activity
GO:0005524; Molecular function:ATP binding
GO:0003677; Molecular function:DNA binding
GO:0051539; Molecular function:4 iron, 4 sulfur cluster binding

Cross-references [?]

PROSITE PS51193; HELICASE_ATP_BIND_2; 1;
PROSITE PS51194; HELICASE_CTER; 1;
Pfam PF00270; DEAD; 1;
Pfam PF06733; DEAD_2; 1;
Pfam PF13307; Helicase_C_2; 1;

Features [?]

From: DING_ECOLI (P27296)
Key From To Description Tag Condition FTGroup
BINDING 120 120 /ligand="[4Fe-4S] cluster"
/ligand_id="ChEBI:CHEBI:49883"
C
BINDING 194 194 /ligand="[4Fe-4S] cluster"
/ligand_id="ChEBI:CHEBI:49883"
C
BINDING 199 199 /ligand="[4Fe-4S] cluster"
/ligand_id="ChEBI:CHEBI:49883"
C
BINDING 205 205 /ligand="[4Fe-4S] cluster"
/ligand_id="ChEBI:CHEBI:49883"
C

Additional information [?]

Size range 650-780 amino acids
Related rules None
Fusion Nter: None Cter: None



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