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Annotation rule MF_02211 |
General rule information
[?]
Accession |
MF_02211 |
Dates |
19-FEB-2019 (Created) 21-JAN-2020 (Last updated, Version 4) |
Name |
MpaA_carboxypeptidase |
Scope |
Bacteria; Gammaproteobacteria |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=Murein peptide amidase A;
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EC 3.4.17.-;
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AltName:
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Full=Gamma-D-Glu-Dap amidase;
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AltName:
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Full=Zinc metallocarboxypeptidase MpaA;
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Function |
Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap. |
Catalytic activity |
RHEA:28398: H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate = L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate
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case <FTGroup:1>
Cofactor |
Zn(2+) Note: Binds 1 zinc ion per subunit. |
end case
Pathway |
Cell wall degradation; peptidoglycan degradation. |
Subunit |
Homodimer. |
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the peptidase M14 family. |
case <FTGroup:1>
end case
GO:0061473; Molecular function: murein tripeptide carboxypeptidase activity.
case <FTGroup:1>
end case
GO:0009253; Biological process: peptidoglycan catabolic process.
GO:0005737; Cellular component: cytoplasm.
From: MPAA_VIBCB (A7N805) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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METAL
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60
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60
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Zinc; via pros nitrogen
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H
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1
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METAL
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63
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63
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Zinc
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E
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1
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METAL
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168
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168
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Zinc; via pros nitrogen
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H
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1
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Additional information
[?]
Size range |
220-280 amino acids |
Related rules |
None |
Fusion |
None |