HAMAP rule MF_02227
General rule information
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| Accession | MF_02227 |
| Dates | 19-SEP-2019 (Created) 1-JUN-2023 (Last updated, Version 7) |
| Name | RPE |
| Scope | Archaea
Bacteria |
| Template | P0AG07 (RPE_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. |
| Catalytic activity | RHEA:13677: D-ribulose 5-phosphate = D-xylulose 5-phosphate
EC 5.1.3.1 |
| Cofactor | a divalent metal cation Note: Binds 1 divalent metal cation per subunit. |
| Pathway | Carbohydrate degradation. |
| Similarity | Belongs to the ribulose-phosphate 3-epimerase family. |
Keywords
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Gene Ontology
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GO:0046872; Molecular function: metal ion binding.
GO:0004750; Molecular function: D-ribulose-phosphate 3-epimerase activity.
GO:0019323; Biological process: pentose catabolic process.
GO:0004750; Molecular function: D-ribulose-phosphate 3-epimerase activity.
GO:0019323; Biological process: pentose catabolic process.
Cross-references
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| PROSITE | PS01085; RIBUL_P_3_EPIMER_1; 1; |
| PS01086; RIBUL_P_3_EPIMER_2; 1; | |
| Pfam | PF00834; Ribul_P_3_epim; 1; |
| NCBIfam | TIGR01163; rpe; 1; |
| PIRSF | PIRSF001461; RPE; 1; |
Features
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| From: RPE_ECOLI (P0AG07) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING (Optional) | 144 | 147 | /ligand="substrate | G-[FY]-x-G | ||||||||
| BINDING (Optional) | 177 | 179 | /ligand="substrate | D-G-G | ||||||||
| BINDING (Optional) | 199 | 200 | /ligand="substrate | [GA]-S | ||||||||
| ACT_SITE | 36 | 36 | Proton acceptor | D | ||||||||
| ACT_SITE | 177 | 177 | Proton donor | D | ||||||||
| BINDING | 34 | 34 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240 | H | 1 | |||||||
| BINDING | 36 | 36 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240 | D | 1 | |||||||
| BINDING | 68 | 68 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240 | H | 1 | |||||||
| BINDING | 177 | 177 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240 | D | 1 | |||||||
| BINDING (Optional) | 9 | 9 | /ligand="substrate | S | ||||||||
| BINDING (Optional) | 68 | 68 | /ligand="substrate | H | ||||||||
Additional information
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| Size range | 200-280 amino acids |
| Related rules | None |
| Fusion | None |