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HAMAP rule MF_02227

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General rule information [?]

Accession MF_02227
Dates 19-SEP-2019 (Created)
1-JUN-2023 (Last updated, Version 7)
Name RPE
Scope(s) Archaea
Template(s) P0AG07 (RPE_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_02227 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RPE
Protein name RecName: Full=Ribulose-phosphate 3-epimerase;
Gene name Name=rpe;

Comments [?]

FUNCTIONCatalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate.
CATALYTIC ACTIVITY Reaction=D-ribulose 5-phosphate = D-xylulose 5-phosphate; Xref=Rhea:RHEA:13677, ChEBI:CHEBI:57737, ChEBI:CHEBI:58121; EC=;
COFACTOR Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Note=Binds 1 divalent metal cation per subunit.;
PATHWAYCarbohydrate degradation.
SIMILARITYBelongs to the ribulose-phosphate 3-epimerase family.

Keywords [?]

Gene Ontology [?]

GO:0046872; Molecular function:metal ion binding
GO:0004750; Molecular function:D-ribulose-phosphate 3-epimerase activity
GO:0019323; Biological process:pentose catabolic process

Cross-references [?]

Pfam PF00834; Ribul_P_3_epim; 1;
NCBIfam TIGR01163; rpe; 1;
PIRSF PIRSF001461; RPE; 1;

Features [?]

From: RPE_ECOLI (P0AG07)
Key From To Description Tag Condition FTGroup
BINDING 144 147 /ligand="substrate" G-[FY]-x-G
BINDING 177 179 /ligand="substrate" D-G-G
BINDING 199 200 /ligand="substrate" [GA]-S
ACT_SITE 36 36 /note="Proton acceptor" D
ACT_SITE 177 177 /note="Proton donor" D
BINDING 34 34 /ligand="a divalent metal cation"
H 1
BINDING 36 36 /ligand="a divalent metal cation"
D 1
BINDING 68 68 /ligand="a divalent metal cation"
H 1
BINDING 177 177 /ligand="a divalent metal cation"
D 1
BINDING 9 9 /ligand="substrate" S
BINDING 68 68 /ligand="substrate" H

Additional information [?]

Size range 200-280 amino acids
Related rules None
Fusion Nter: None Cter: None

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