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HAMAP rule MF_02229

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General rule information [?]

Accession MF_02229
Dates 25-SEP-2019 (Created)
1-JUN-2023 (Last updated, Version 5)
Name Deoxyribose1P_isomerase
Template P0DTQ1 (DRDI_BACT7)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=5-deoxyribose 1-phosphate isomerase;
EC 5.3.1.-;
Gene name

Comments [?]

Function Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1-phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites.
Catalytic activity RHEA:61296: 5-deoxy-alpha-D-ribose 1-phosphate = 5-deoxy-D-ribulose 1-phosphate
PhysiologicalDirection=left-to-right (RHEA:61297)
Pathway Carbohydrate degradation.
Similarity Belongs to the EIF-2B alpha/beta/delta subunits family. DrdI subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016861; Molecular function: intramolecular oxidoreductase activity, interconverting aldoses and ketoses.
GO:0019323; Biological process: pentose catabolic process.

Cross-references [?]

Pfam PF01008; IF-2B; 1;
NCBIfam TIGR00524; eIF-2B_rel; 1;
TIGR00512; salvage_mtnA; 1;

Features [?]

Key     From     To       Description   Tag   Condition   FTGroup
BINDING     49     51       /ligand="substrate     R-G-A  
BINDING     250     251       /ligand="substrate     N-K  
ACT_SITE     240     240       Proton donor     D  
BINDING     92     92       /ligand="substrate     R  
BINDING     199     199       /ligand="substrate     Q  
SITE     160     160       Transition state stabilizer     C  

Additional information [?]

Size range 340-390 amino acids
Related rules MF_01678 (MTNA)
Fusion None