HAMAP rule MF_02236
General rule information
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Accession | MF_02236 |
Dates | 16-OCT-2019 (Created) 19-NOV-2022 (Last updated, Version 4) |
Name | ACDase |
Scope | Bacteria |
Template | Q8P8J5 (ACDAS_XANCP) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline. This is a step in an alternative arginine biosynthesis pathway. |
Catalytic activity | RHEA:61092: H2O + N(2)-acetyl-L-citrulline = acetate + L-citrulline
PhysiologicalDirection=left-to-right (RHEA:61093) |
Cofactor | Co(2+) Note: Binds 1 Co(2+) ion per subunit. |
Pathway | Amino-acid biosynthesis; L-arginine biosynthesis. |
Similarity | Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily. |
Keywords
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Gene Ontology
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GO:0016811; Molecular function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides.
GO:0050897; Molecular function: cobalt ion binding.
GO:0006526; Biological process: arginine biosynthetic process.
GO:0050897; Molecular function: cobalt ion binding.
GO:0006526; Biological process: arginine biosynthetic process.
Cross-references
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Features
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From: ACDAS_XANCP (Q8P8J5) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 130 | 130 | Proton donor/acceptor | E | ||||||||
BINDING | 72 | 72 | /ligand="Co(2+)" /ligand_id="ChEBI:CHEBI:48828 | H | ||||||||
BINDING | 103 | 103 | /ligand="Co(2+)" /ligand_id="ChEBI:CHEBI:48828 | D | ||||||||
BINDING | 155 | 155 | /ligand="Co(2+)" /ligand_id="ChEBI:CHEBI:48828 | E |
Additional information
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Size range | 335-420 amino acids |
Related rules | None |
Fusion | None |