HAMAP rule MF_02238

General rule information [?]

Accession	MF_02238
Dates	3-DEC-2019 (Created) 19-NOV-2022 (Last updated, Version 3)

Name

DSD

Scope

Bacteria

Templates

Q88JU3 (DSD_PSEPK); Q9I6P6 (DSD_PSEAE): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

DSD

Protein name

RecName:		Full=3-dehydroshikimate dehydratase;
		Short=DSD;
		EC 4.2.1.118;

Comments [?]

Function	Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.
Catalytic activity	RHEA:24848: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O EC 4.2.1.118 PhysiologicalDirection=left-to-right (RHEA:24849)
Cofactor	a divalent metal cation
Pathway	Aromatic compound metabolism; 3,4-dihydroxybenzoate biosynthesis.
Similarity	Belongs to the bacterial two-domain DSD family.

Keywords [?]

Gene Ontology [?]

GO:0046565; Molecular function: 3-dehydroshikimate dehydratase activity.
GO:0046872; Molecular function: metal ion binding.

Cross-references [?]

Features [?]

From: DSD_PSEPK (Q88JU3)

Key From To Description Tag Condition FTGroup

BINDING 134 134 /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" /ligand_note="catalytic E 1

BINDING 165 165 /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" /ligand_note="catalytic D 1

BINDING 191 191 /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" /ligand_note="catalytic Q 1

BINDING 239 239 /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" /ligand_note="catalytic E 1

BINDING (Optional) 443 443 /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 H 2

BINDING (Optional) 521 521 /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 H 2

BINDING (Optional) 599 599 /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 E 2

Additional information [?]