HAMAP rule MF_02238
General rule information
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Accession | MF_02238 |
Dates | 3-DEC-2019 (Created) 19-NOV-2022 (Last updated, Version 3) |
Name | DSD |
Scope | Bacteria |
Templates | Q88JU3 (DSD_PSEPK); Q9I6P6 (DSD_PSEAE): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Comments
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Function | Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways. |
Catalytic activity | RHEA:24848: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O
EC 4.2.1.118 PhysiologicalDirection=left-to-right (RHEA:24849) |
Cofactor | a divalent metal cation |
Pathway | Aromatic compound metabolism; 3,4-dihydroxybenzoate biosynthesis. |
Similarity | Belongs to the bacterial two-domain DSD family. |
Keywords
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Gene Ontology
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GO:0046565; Molecular function: 3-dehydroshikimate dehydratase activity.
GO:0046872; Molecular function: metal ion binding.
GO:0046872; Molecular function: metal ion binding.
Cross-references
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Features
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From: DSD_PSEPK (Q88JU3) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 134 | 134 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" /ligand_note="catalytic | E | 1 | |||||||
BINDING | 165 | 165 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" /ligand_note="catalytic | D | 1 | |||||||
BINDING | 191 | 191 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" /ligand_note="catalytic | Q | 1 | |||||||
BINDING | 239 | 239 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" /ligand_note="catalytic | E | 1 | |||||||
BINDING (Optional) | 443 | 443 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 | H | 2 | |||||||
BINDING (Optional) | 521 | 521 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 | H | 2 | |||||||
BINDING (Optional) | 599 | 599 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 | E | 2 |
Additional information
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Size range | 570-690 amino acids |
Related rules | None |
Fusion | None |