HAMAP rule MF_02239
General rule information
[?]
Accession | MF_02239 |
Dates | 12-DEC-2019 (Created) 1-JUN-2023 (Last updated, Version 5) |
Name | HemJ |
Scope | Bacteria |
Template | P72793 (HEMJ_SYNY3) |
Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
Protein name |
|
Comments
[?]
Function | Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX. |
Catalytic activity | RHEA:62000: 3 A + protoporphyrinogen IX = 3 AH2 + protoporphyrin IX |
Cofactor | heme b Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit. |
Pathway | Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1. |
Subunit | Homodimer. |
Subcellular location | Cell membrane; Multi-pass membrane protein. |
Similarity | Belongs to the HemJ family. |
Keywords
[?]
Gene Ontology
[?]
GO:0070818; Molecular function: protoporphyrinogen oxidase activity.
GO:0006779; Biological process: porphyrin-containing compound biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
GO:0006779; Biological process: porphyrin-containing compound biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
Cross-references
[?]
Pfam | PF03653; UPF0093; 1; |
PIRSF | PIRSF004638; UCP004638; 0-1; |
NCBIfam | TIGR00701; TIGR00701; 1; |
Computed features
[?]
General | Transmembrane; -; 4-5; trigger=yes; |
Features
[?]
From: HEMJ_SYNY3 (P72793) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 27 | 27 | /ligand="heme" /ligand_id="ChEBI:CHEBI:30413" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue | H | ||||||||
BINDING | 108 | 108 | /ligand="heme" /ligand_id="ChEBI:CHEBI:30413" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue | K |
Additional information
[?]
Size range | 145-210 amino acids |
Related rules | None |
Fusion | None |