HAMAP rule MF_03013

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_03013
Accession	MF_03013
Dates	12-FEB-2009 (Created) 20-NOV-2019 (Last updated, Version 11)
Name	CLU
Scope(s)	Eukaryota
Template(s)	O15818; A1ZAB5; Q03690; [ Recover all ]
Triggered by	HAMAP; MF_03013 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	CLU
case <OC:Fungi>
Protein name	RecName: Full=Clustered mitochondria protein homolog; AltName: Full=Protein TIF31 homolog;
else case <OC:Drosophilidae>
Protein name	RecName: Full=Protein clueless; AltName: Full=Clustered mitochondria protein homolog;
else
Protein name	RecName: Full=Clustered mitochondria protein homolog;
end case
case <OC:Fungi>
Gene name	Name=CLU1; Synonyms=TIF31;
else case <OC:Drosophilidae>
Gene name	Name=clu;
else case <OC:Caenorhabditis>
Gene name	Name=clu-1;
else case <OC:Amoebozoa>
Gene name	Name=cluA;
end case

Comments [?]

case <OC:Vertebrata>
FUNCTION	mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.
SUBCELLULAR LOCATION	Cytoplasm. Cytoplasmic granule.
else
FUNCTION	mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
SUBCELLULAR LOCATION	Cytoplasm.
end case
case <OC:Fungi>
SUBUNIT	May associate with the eukaryotic translation initiation factor 3 (eIF-3) complex.
end case
SIMILARITY	Belongs to the CLU family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm

GO:0007005; Biological process:mitochondrion organization

Cross-references [?]

Features [?]

Additional information [?]