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HAMAP rule MF_03013

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General rule information [?]

Accession MF_03013
Dates 12-FEB-2009 (Created)
20-NOV-2019 (Last updated, Version 10)
Name CLU
Scope(s) Eukaryota
Template(s) O15818 (CLU_DICDI); A1ZAB5 (CLU_DROME); Q03690 (CLU_YEAST); [ Recover all ]
Triggered by HAMAP; MF_03013 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CLU
case <OC:Fungi>
Protein name RecName: Full=Clustered mitochondria protein homolog;
AltName: Full=Protein TIF31 homolog;
else case <OC:Drosophilidae>
Protein name RecName: Full=Protein clueless;
AltName: Full=Clustered mitochondria protein homolog;
else
Protein name RecName: Full=Clustered mitochondria protein homolog;
end case
case <OC:Fungi>
Gene name Name=CLU1; Synonyms=TIF31;
else case <OC:Drosophilidae>
Gene name Name=clu;
else case <OC:Caenorhabditis>
Gene name Name=clu-1;
else case <OC:Amoebozoa>
Gene name Name=cluA;
end case

Comments [?]

case <OC:Vertebrata>
FUNCTIONmRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.
SUBCELLULAR LOCATIONCytoplasm. Cytoplasmic granule.
else
FUNCTIONmRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
SUBCELLULAR LOCATIONCytoplasm.
end case
case <OC:Fungi>
SUBUNITMay associate with the eukaryotic translation initiation factor 3 (eIF-3) complex.
end case
SIMILARITYBelongs to the CLU family.

Keywords [?]


Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm
GO:0007005; Biological process:mitochondrion organization

Cross-references [?]

PROSITE PS51823; CLU; 1;
PROSITE PS50293; TPR_REGION; 1;
PROSITE PS50005; TPR; 1;
PROSITE PS50312; ASP_RICH; 0-unlimited;
PROSITE PS50313; GLU_RICH; 0-unlimited;
PROSITE PS50318; LYS_RICH; 0-unlimited;
PROSITE PS50323; ARG_RICH; 0-unlimited;
Pfam PF13236; CLU; 1;
Pfam PF00515; TPR_1; 1;
REP Repeat_TPR; TPR; 1-8;
General Coiled_coil; -; 0-unlimited;

Features [?]


Additional information [?]

Size range 1135-1502 amino acids
Related rules None
Fusion Nter: None Cter: None



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