HAMAP rule MF_03025
General rule information
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Accession |
MF_03025 |
Dates |
9-OCT-2012 (Created) 19-NOV-2022 (Last updated, Version 12) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Katanin p60 ATPase-containing subunit A-like 2;
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Short=Katanin p60 subunit A-like 2;
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EC 5.6.1.1;
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AltName:
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Full=p60 katanin-like 2;
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Function |
Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. |
Catalytic activity |
Reaction=n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.; EC=5.6.1.1; |
Subcellular location |
Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis. |
Similarity |
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily. |
From: KATL2_HUMAN (Q8IYT4) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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BINDING
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294
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301
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/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616
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G-P-P-[GD]-[TLN]-G-K-T
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Additional information
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Size range |
403-603 amino acids |
Related rules |
None |
Fusion |
None |