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Annotation rule MF_03043 |
General rule information
[?]
Accession |
MF_03043 |
Dates |
11-AUG-2009 (Created) 20-NOV-2019 (Last updated, Version 10) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=Queuine tRNA-ribosyltransferase accessory subunit 2;
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AltName:
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Full=Queuine tRNA-ribosyltransferase domain-containing protein 1;
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case <OC:Vertebrata>
else case <OC:Caenorhabditis>
end case
Function |
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). |
case <FTGroup:1>
Cofactor |
Zn(2+) Note: Binds 1 zinc ion per subunit. |
end case
case <OC:Vertebrata>
Subunit |
Heterodimer of a catalytic subunit @gn(QTRT1) and an accessory subunit @gn(QTRT2). |
Subcellular location |
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Note=May associate with the mitochondrion outer membrane. |
else
Subunit |
Heterodimer of a catalytic subunit and an accessory subunit. |
Subcellular location |
Cytoplasm. |
end case
Similarity |
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. |
case <OC:Vertebrata>
end case
case <FTGroup:1>
end case
case <OC:Vertebrata>
GO:0005741; Cellular component: mitochondrial outer membrane.
end case
GO:0008479; Molecular function: queuine tRNA-ribosyltransferase activity.
GO:0101030; Biological process: tRNA-guanine transglycosylation.
From: QTRT2_MOUSE (B8ZXI1) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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METAL
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351
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351
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Zinc
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C
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1
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METAL
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353
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353
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Zinc
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C
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1
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METAL
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356
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356
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Zinc
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C
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1
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METAL
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382
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382
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Zinc; via pros nitrogen
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H
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1
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Additional information
[?]
Size range |
369-432 amino acids |
Related rules |
None |
Fusion |
None |