HAMAP rule MF_03103
General rule information
[?]
Accession | MF_03103 |
Dates | 14-AUG-2009 (Created) 29-SEP-2022 (Last updated, Version 11) |
Name | Mmm1 |
Scope | Eukaryota; Fungi |
Template | P41800 (MMM1_YEAST) |
Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
case <OC:Saccharomyces>
Protein name |
|
else
Protein name |
|
end case
Gene name |
|
Comments
[?]
Function | Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The @gn(MDM12)- |
Subunit | Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of |
Subcellular location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids. |
Similarity | Belongs to the MMM1 family. |
Keywords
[?]
Gene Ontology
[?]
GO:0005789; Cellular component: endoplasmic reticulum membrane.
GO:0032865; Cellular component: ERMES complex.
GO:0000002; Biological process: mitochondrial genome maintenance.
GO:0045040; Biological process: protein insertion into mitochondrial outer membrane.
GO:0032865; Cellular component: ERMES complex.
GO:0000002; Biological process: mitochondrial genome maintenance.
GO:0045040; Biological process: protein insertion into mitochondrial outer membrane.
Cross-references
[?]
Computed features
[?]
General | Transmembrane; -; 0-1; |
Features
[?]
From: MMM1_YEAST (P41800) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TOPO_DOM | Nter | 100 | Lumenal | |||||||||
TRANSMEM | 101 | 121 | Helical | |||||||||
TOPO_DOM | 122 | Cter | Cytoplasmic |
Additional information
[?]
Size range | 291-591 amino acids |
Related rules | None |
Fusion | None |