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Annotation rule MF_03103 |
Accession | MF_03103 |
Dates | 14-AUG-2009 (Created) 20-NOV-2019 (Last updated, Version 10) |
Name | Mmm1 |
Scope | Eukaryota; Fungi |
Template | P41800 (MMM1_YEAST) |
Triggered by |
Identifier |
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Protein name |
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Protein name |
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Gene name |
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Function | Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The @gn(MDM12)- |
Subunit | Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of |
Subcellular location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids. |
Similarity | Belongs to the MMM1 family. |
General | Transmembrane; -; 0-1; |
From: MMM1_YEAST (P41800) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TOPO_DOM | Nter | 100 | Lumenal | |||||||||
TRANSMEM | 101 | 121 | Helical | |||||||||
TOPO_DOM | 122 | Cter | Cytoplasmic |
Size range | 291-591 amino acids |
Related rules | None |
Fusion | None |