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HAMAP rule MF_03111

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General rule information [?]

Accession MF_03111
Dates 8-OCT-2009 (Created)
20-NOV-2019 (Last updated, Version 6)
Name Coq4
Scope
Eukaryota
Template O13525 (COQ4_YEAST)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
COQ4
case <OC:Fungi> or <OC:Caenorhabditis>
Protein name
RecName: Full=Ubiquinone biosynthesis protein , mitochondrial;
AltName: Full=Coenzyme Q biosynthesis protein 4;
else
Protein name
RecName: Full=Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial;
AltName: Full=Coenzyme Q biosynthesis protein 4 homolog;
end case
case <OC:Vertebrata> or <OC:Fungi> or <OC:Dictyostelium>
Gene name
COQ4
else case <OC:Caenorhabditis>
Gene name
coq-4
end case

Comments [?]

case <OC:Saccharomyces>
Function Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of COQ3, COQ4, COQ6, COQ7 and COQ9 polypeptides.
else
Function Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
end case
Pathway Cofactor biosynthesis; ubiquinone biosynthesis.
case <OC:Saccharomyces>
Subunit Component of a multi-subunit COQ enzyme complex, composed of at least @gn(COQ3), @gn(COQ4), @gn(COQ5), @gn(COQ6), @gn(COQ7) and @gn(COQ9). Interacts with COQ3.
else case <OC:Vertebrata> or <OC:Fungi> and not <OC:Saccharomyces>
Subunit Component of a multi-subunit COQ enzyme complex, composed of at least @gn(COQ3), @gn(COQ4), @gn(COQ5), @gn(COQ6), @gn(COQ7) and @gn(COQ9).
else
Subunit Component of a multi-subunit COQ enzyme complex.
end case
Subcellular location Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
case not <AnyFeature:TransitM>
Miscellaneous This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case
Similarity Belongs to the COQ4 family.

Keywords [?]

Membrane
Mitochondrion
Mitochondrion inner membrane
Ubiquinone biosynthesis

Gene Ontology [?]

GO:0031314; Cellular component: extrinsic component of mitochondrial inner membrane.
GO:0006744; Biological process: ubiquinone biosynthetic process.

Cross-references [?]

Pfam PF05019; Coq4; 1;

Computed features [?]

General TransitM; -; 0-1; trigger=yes;

Additional information [?]

Size range 187-369 amino acids
Related rules None
Fusion None


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