Home  |  Contact
Annotation rule MF_03138
Send feedback

General rule information [?]

Accession MF_03138
Dates 2-NOV-2010 (Created)
20-NOV-2019 (Last updated, Version 8)
Name GUFP
Scope
Eukaryota; Viridiplantae
Plastid
Template Q9FNM5 (GUFP_ARATH)
case <OC:Eukaryota> or <OG:Plastid>
Triggered by
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GUFP
case <OG:Organellar chromatophore>
Protein name
RecName: Full=Translation factor GUF1 homolog, organellar chromatophore;
EC 3.6.5.n1;
AltName: Full=Elongation factor 4 homolog;
Short=EF-4;
AltName: Full=GTPase GUF1 homolog;
AltName: Full=Ribosomal back-translocase;
else
Protein name
RecName: Full=Translation factor GUF1 homolog, chloroplastic;
EC 3.6.5.n1;
AltName: Full=Elongation factor 4 homolog;
Short=EF-4;
AltName: Full=GTPase GUF1 homolog;
AltName: Full=Ribosomal back-translocase;
end case
case <OG:Organellar chromatophore>
Gene name
lepA
end case

Comments [?]

case <OG:Organellar chromatophore>
Function Promotes protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.
else
Function Promotes chloroplast protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.
end case
Catalytic activity RHEA:19669: GTP + H2O = GDP + H(+) + phosphate
EC 3.6.5.n1
case <OG:Organellar chromatophore>
Subcellular location Plastid, organellar chromatophore.
else
Subcellular location Plastid, chloroplast.
end case
case not <OG:Organellar chromatophore> and not <AnyFeature:TransitC>
Miscellaneous This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case
Similarity Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.

Keywords [?]

case <OG:Organellar chromatophore>
Organellar chromatophore
else
Chloroplast
end case
Plastid
GTP-binding
Hydrolase
Nucleotide-binding
Protein biosynthesis

Gene Ontology [?]

case <OG:Organellar chromatophore>
GO:0070111; Cellular component: organellar chromatophore.
else
GO:0009507; Cellular component: chloroplast.
end case
GO:0005525; Molecular function: GTP binding.
GO:0003924; Molecular function: GTPase activity.
GO:0045727; Biological process: positive regulation of translation.

Cross-references [?]

Pfam PF00679; EFG_C; 1;
PF00009; GTP_EFTU; 1;
PF03144; GTP_EFTU_D2; 1;
PF06421; LepA_C; 1;
PRINTS PR00315; ELONGATNFCT; 1;
TIGRFAMs TIGR01393; LepA; 1;
TIGR00231; Small_GTP; 1;
PROSITE PS00301; G_TR_1; 1;
PS51722; G_TR_2; 1;

Computed features [?]

case not <OG:Organellar chromatophore>
General TransitC; -; 0-1; trigger=yes;
end case

Features [?]

From: GUFP_ARATH (Q9FNM5)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     93     100       GTP     [AS]-H-[IV]-D-[HS]-G-K-[ST]  
NP_BIND     158     162       GTP     D-T-[CP]-G-H  
NP_BIND     212     215       GTP     [NT]-K-[IMV]-D  

Additional information [?]

Size range 602-735 amino acids
Related rules MF_03138 (GUFP)
Fusion None


View rule in raw text format (no links)