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Annotation rule MF_03165 |
Accession | MF_03165 |
Dates | 13-FEB-2013 (Created) 20-NOV-2019 (Last updated, Version 10) |
Name | Top6B_plant |
Scope | Eukaryota; Viridiplantae |
Templates | O05207 (TOP6B_SACSH); Q9C5V6 (TOP6B_ARATH); B8BDQ4 (TOP6B_ORYSI): [Recover all] |
Triggered by |
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Protein name |
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Gene name |
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Function | Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP. |
Catalytic activity | Reaction=ATP-dependent breakage, passage and rejoining of double-stranded DNA.; EC=5.6.2.2; |
Subunit | Homodimer. Heterotetramer of two TOP6A and two TOP6B subunits. |
Subcellular location | Nucleus. |
Similarity | Belongs to the TOP6B family. |
From: TOP6B_SACSH (O05207) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
NP_BIND (Optional) | 97 | 98 | ATP | [ST]-[KR] | ||||||||
NP_BIND (Optional) | 106 | 113 | ATP | G-x-x-G-[LIV]-G-x-[KSA] | ||||||||
BINDING (Optional) | 42 | 42 | ATP | N | ||||||||
BINDING (Optional) | 76 | 76 | ATP | D | ||||||||
BINDING (Optional) | 427 | 427 | ATP | K |
Size range | 475-842 amino acids |
Related rules | None |
Fusion | None |