HAMAP rule MF_03167
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_03167 |
| Accession | MF_03167 |
| Dates | 22-FEB-2013 (Created)
1-JUN-2023 (Last updated, Version 13) |
| Name | YchF_OLA1_ATPase_euk |
| Scope(s) |
Eukaryota |
| Template(s) | Q9NTK5 (OLA1_HUMAN); P0ABU2 (YCHF_ECOLI); [ Recover all ] |
| Triggered by |
case c? <OC:Eukaryota>
HAMAP; MF_00944 (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| Identifier | OLA1 |
| Protein name | RecName: Full=Obg-like ATPase 1; |
| case <OC:Vertebrata> or <OC:Saccharomycotina> | |
| Gene name | Name=OLA1; |
| end case | |
Comments
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| FUNCTION | Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. |
| SUBUNIT | Monomer. |
| case <OC:Vertebrata> | |
| SUBCELLULAR LOCATION | Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Predominantly cytoplasmic, shuttles between the nucleus and the cytoplasm. |
| else | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| end case | |
| SIMILARITY | Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. |
Keywords
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| ATP-binding | |
| Cytoplasm | |
| Hydrolase | |
| Nucleotide-binding | |
| case <OC:Vertebrata> | |
| Nucleus | |
| end case | |
Gene Ontology
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| GO:0005737; Cellular component:cytoplasm | |
| case <OCellular component:Vertebrata> | |
| GO:0005730; Cellular component:nucleolus | |
| end case | |
| GO:0005524; Molecular function:ATP binding | |
| GO:0016887; Molecular function:ATP hydrolysis activity | |
| GO:0043023; Molecular function:ribosomal large subunit binding | |
| GO:0043022; Molecular function:ribosome binding | |
Cross-references
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| Pfam | PF01926; MMR_HSR1; 1; |
| Pfam | PF06071; YchF-GTPase_C; 1; |
| PRINTS | PR00326; GTP1OBG; 1; |
| NCBIfam | TIGR00092; TIGR00092; 1; |
| PIRSF | PIRSF006641; CHP00092; 1; |
| PROSITE | PS51710; G_OBG; 1; |
Features
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| From: OLA1_HUMAN (Q9NTK5) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 32 | 37 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
N-x-G-K-[ST]-[TS] | ||||||||
| BINDING | 231 | 231 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
[LMV] | ||||||||
| case <OC:Vertebrata> | ||||||||||||
| MOTIF | 267 | 274 | /note="Nuclear export signal" | L-E-L-[KRN]-L-Q-[ED]-[LM] | ||||||||
| end case | ||||||||||||
Additional information
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| Size range | 346-487 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |