HAMAP rule MF_03229
General rule information
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Accession | MF_03229 |
Dates | 11-NOV-2020 (Created) 11-NOV-2020 (Last updated, Version 2) |
Name | FITM1 |
Scope | Eukaryota; Euteleostomi |
Template | A5D6W6 (FITM1_HUMAN) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
|
case <FTGroup:1>
Protein name |
|
else
Protein name |
|
end case
Gene name |
|
Comments
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case <FTGroup:1> and <OC:Mammalia>
Function | Plays an important role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. Directly binds to diacylglycerol (DAGs) and triacylglycerol. |
else case <FTGroup:1>
Function | Plays an important role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol. |
else
Function | May play a role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol. |
end case
Subcellular location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Similarity | Belongs to the FIT family. FIT1 subfamily. |
Keywords
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Gene Ontology
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GO:0005789; Cellular component: endoplasmic reticulum membrane.
GO:0140042; Biological process: lipid droplet formation.
GO:0140042; Biological process: lipid droplet formation.
Cross-references
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Pfam | PF10261; Scs3p; 0-1; |
Computed features
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General | Transmembrane; -; 7; |
Features
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From: FITM1_HUMAN (A5D6W6) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 186 | 186 | H | 1 | ||||||||
ACT_SITE | 244 | 244 | H | 1 |
case <FTGroup:1>
end case
Additional information
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Size range | 253-327 amino acids |
Related rules | None |
Fusion | None |