HAMAP rule MF_04027
General rule information
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| Accession | MF_04027 |
| Dates | 28-APR-2016 (Created)
4-JUN-2021 (Last updated, Version 4) |
| Name | HSV_RIR1_betahv |
| Scope(s) |
Viruses Betaherpesvirinae |
| Template(s) | Q6SW87 (RIR1_HCMVM); [ Recover all ] |
| Triggered by |
HAMAP; MF_04027 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RIR1 |
| Protein name | RecName: Full=Ribonucleoside-diphosphate reductase large subunit-like protein; |
| Gene name | Name=RIR1; |
Comments
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| FUNCTION | Does not possess a ribonucleotide reductase activity. Betaherpesviruses probably use another strategy to expand the dNTP pool in a quiescent host cell. |
| SUBCELLULAR LOCATION | Virion. Host cytoplasm. |
| SIMILARITY | Belongs to the ribonucleoside diphosphate reductase large chain family. |
| CAUTION | Lacks the conserved sequence Asn-x-Cys-x-Glu essential for ribonucleotide reductase activity. |
Keywords
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Gene Ontology
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| GO:0044423; Cellular component:virion component |
Cross-references
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| PROSITE | PS00089; RIBORED_LARGE; 1; |
| Pfam | PF02867; Ribonuc_red_lgC; 1; |
| Pfam | PF12721; RHIM; 1; |
| Pfam | PF00317; Ribonuc_red_lgN; 1; |
| PRINTS | PR01183; RIBORDTASEM1; 1; |
Features
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Additional information
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| Size range | 804-1174 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |