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Annotation rule MF_04030 |
Accession | MF_04030 |
Dates | 9-MAY-2016 (Created) 20-NOV-2019 (Last updated, Version 3) |
Name | HSV_HELI |
Scope | Viruses; Herpesviridae |
Template | P10189 (HELI_HHV11) |
Triggered by |
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Protein name |
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Gene name |
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Function | Component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase synthesizes short RNA primers on the lagging strand that the polymerase elongates using dNTPs. Possesses helicase-like motifs and therefore may act as the helicase subunit of the complex. |
Subunit | Associates with the primase and the primase-associated factor to form the helicase-primase complex. |
Subcellular location | Host nucleus. |
Similarity | Belongs to the herpesviridae helicase family. |
Pfam | PF02689; Herpes_Helicase; 1; |
From: HELI_HHV11 (P10189) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
NP_BIND | 97 | 104 | ATP | G-x-A-G-x-G-K-[ST] |
Size range | 781-956 amino acids |
Related rules | None |
Fusion | None |