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Annotation rule MF_04031 |
Accession | MF_04031 |
Dates | 9-MAY-2016 (Created) 20-NOV-2019 (Last updated, Version 4) |
Name | HSV_DUT |
Scope | Viruses; Herpesviridae |
Template | P10234 (DUT_HHV11) |
Triggered by |
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Protein name |
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Gene name |
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Function | Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA. |
Catalytic activity | RHEA:10248: dUTP + H2O = diphosphate + dUMP + H(+)
EC 3.6.1.23 |
Cofactor | Mg(2+) |
Similarity | Belongs to the dUTPase family. |
From: DUT_HHV11 (P10234) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION | 260 | 262 | Substrate binding | R-S-[SG] | ||||||||
REGION | 366 | 367 | Substrate binding | F-G |
Size range | 268-436 amino acids |
Related rules | None |
Fusion | None |