HAMAP rule MF_04035

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_04035
Accession	MF_04035
Dates	30-AUG-2016 (Created) 29-SEP-2022 (Last updated, Version 5)
Name	HSV_GM
Scope(s)	Viruses Herpesviridae
Template(s)	P04288; P16733; [ Recover all ]
Triggered by	HAMAP; MF_04035 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	GM
Protein name	RecName: Full=Envelope glycoprotein M; Short=gM;
Gene name	Name=gM;

Comments [?]

FUNCTION	Envelope glycoprotein important for virion assembly and egress. Plays a role in the correct incorporation of gH-gL into virion membrane. Directs the glycoprotein N (gN) to the host trans-Golgi network.
SUBUNIT	Interacts (via N-terminus) with gN (via N-terminus). The gM-gN heterodimer forms the gCII complex.
SUBCELLULAR LOCATION	Virion membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network. Host endosome membrane; Multi-pass membrane protein. Host nucleus inner membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein accumulates in the trans-Golgi network where secondary envelopment occurs.
SIMILARITY	Belongs to the herpesviridae glycoprotein M family.

Keywords [?]

Gene Ontology [?]

GO:0044175; Cellular component:host cell endosome membrane

GO:0044178; Cellular component:host cell Golgi membrane

GO:0044201; Cellular component:host cell nuclear inner membrane

GO:0016020; Cellular component:membrane

GO:0019031; Cellular component:viral envelope

GO:0055036; Cellular component:virion membrane

Cross-references [?]

Features [?]

From: GM_HHV11 (P04288)

Key

From

Description

Tag

Condition

FTGroup

DISULFID

/note="Interchain (with gN)"

Additional information [?]