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Annotation rule MF_04039
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General rule information [?]

Accession MF_04039
Dates 19-SEP-2016 (Created)
20-NOV-2019 (Last updated, Version 3)
Viruses; Herpesviridae
Template P10200 (CEP2_HHV11)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Cytoplasmic envelopment protein 2;

Comments [?]

Function Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid. Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.
Subunit Interacts with cytoplasmic envelopment protein 3 and with the capsid.
Subcellular location Virion tegument. Host cytoplasm. Host nucleus. Note=Localizes in the host nucleus up to 18 hours postinfection, but at later times localizes to punctate, cytoplasmic structures.
Similarity Belongs to the herpesviridae cytoplasmic envelopment protein 2 family.

Keywords [?]

Gene Ontology [?]

GO:0030430; Cellular component: host cell cytoplasm.
GO:0042025; Cellular component: host cell nucleus.
GO:0019033; Cellular component: viral tegument.

Cross-references [?]

Pfam PF03044; Herpes_UL16; 1;

Additional information [?]

Size range 330-373 amino acids
Related rules None
Fusion None