HAMAP rule MF_04119
General rule information
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| Accession | MF_04119 |
| Dates | 18-JAN-2018 (Created)
23-AUG-2022 (Last updated, Version 5) |
| Name | CAPSID_PROTEIN_T7 |
| Scope(s) |
Viruses Caudoviricetes |
| Template(s) | P19727 (CAPSB_BPT7); [ Recover all ] |
| Triggered by |
HAMAP; MF_04119 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| case <Length>370> | |
| Identifier | CAPSB |
| Protein name | RecName: Full=Minor capsid protein; AltName: Full=Minor head protein; |
| else | |
| Identifier | CAPSA |
| Protein name | RecName: Full=Major capsid protein; AltName: Full=Major head protein; |
| end case | |
Comments
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| case <Length>370> | |
| FUNCTION | Assembles with the major capsid protein to form an icosahedral capsid. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid is formed, encapsidates one single copy of the viral genome. |
| SUBUNIT | Interacts with the connector protein and the major capsid protein. |
| SUBCELLULAR LOCATION | Virion. |
| MISCELLANEOUS | The minor capsid protein is produced by a -1 ribosomal frameshift near the C-terminus of the ORF coding for the major capsid protein, producing a protein with a C-terminal extension compared to the major capsid protein. The major capsid protein is produced by conventional translation of the same ORF. |
| SIMILARITY | Belongs to the T7virus minor capsid protein family. |
| else | |
| FUNCTION | Assembles with the minor capsid protein to form an icosahedral capsid. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid is formed, encapsidates one single copy of the viral genome. |
| SUBUNIT | Homohexamer. Interacts with the connector protein and the minor capsid protein. Interacts with the capsid assembly scaffolding protein; capsid proteins and scaffolding proteins form building blocks that assemble to form the procapsid, each hexamer of the major capsid protein interacting with 2 scaffolding proteins. |
| DOMAIN | The N-terminus interacts with an internal region of the major capsid protein subunit in an adjacent capsomere (intercapsomeric interactions) to stabilize the capsid. |
| SUBCELLULAR LOCATION | Virion. |
| SIMILARITY | Belongs to the T7virus major capsid protein family. |
| end case | |
Keywords
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Gene Ontology
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| GO:0019028; Cellular component:viral capsid |
Cross-references
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| General | Coiled_coil; -; 0-unlimited; |
Features
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Additional information
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| Size range | 1-450 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |