HAMAP rule MF_04119

General rule information [?]

Accession	MF_04119
Dates	18-JAN-2018 (Created) 23-AUG-2022 (Last updated, Version 5)

Name	CAPSID_PROTEIN_T7

Scope

Viruses; Caudoviricetes

Template

P19727 (CAPSB_BPT7)

Triggered by

HAMAP; MF_04119 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

case <Length>370>

Identifier

CAPSB

Protein name

RecName:		Full=Minor capsid protein;
AltName:		Full=Minor head protein;

else

Identifier

CAPSA

Protein name

RecName:		Full=Major capsid protein;
AltName:		Full=Major head protein;

end case

Comments [?]

case <Length>370>

Function	Assembles with the major capsid protein to form an icosahedral capsid. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid is formed, encapsidates one single copy of the viral genome.
Subunit	Interacts with the connector protein and the major capsid protein.
Subcellular location	Virion.
Miscellaneous	The minor capsid protein is produced by a -1 ribosomal frameshift near the C-terminus of the ORF coding for the major capsid protein, producing a protein with a C-terminal extension compared to the major capsid protein. The major capsid protein is produced by conventional translation of the same ORF.
Similarity	Belongs to the T7virus minor capsid protein family.

else

Function	Assembles with the minor capsid protein to form an icosahedral capsid. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid is formed, encapsidates one single copy of the viral genome.
Subunit	Homohexamer. Interacts with the connector protein and the minor capsid protein. Interacts with the capsid assembly scaffolding protein; capsid proteins and scaffolding proteins form building blocks that assemble to form the procapsid, each hexamer of the major capsid protein interacting with 2 scaffolding proteins.
Domain	The N-terminus interacts with an internal region of the major capsid protein subunit in an adjacent capsomere (intercapsomeric interactions) to stabilize the capsid.
Subcellular location	Virion.
Similarity	Belongs to the T7virus major capsid protein family.

end case

Keywords [?]

Capsid protein
Virion

Gene Ontology [?]

GO:0019028; Cellular component: viral capsid.

Computed features [?]

General

Coiled_coil; -; 0-unlimited; trigger=yes;

Additional information [?]

Size range	1-450 amino acids
Related rules	None
Fusion	None

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