HAMAP rule MF_04133
General rule information
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| Accession | MF_04133 |
| Dates | 11-JAN-2019 (Created)
23-AUG-2022 (Last updated, Version 4) |
| Name | CAPSID_LAMBDA |
| Scope(s) |
Viruses Caudoviricetes |
| Template(s) | P03713 (CAPSD_LAMBD); [ Recover all ] |
| Triggered by |
HAMAP; MF_04133 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | CAPSD |
| Protein name | RecName: Full=Major capsid protein; AltName: Full=Major head protein; |
| case <OC:Lambdavirus> | |
| Protein name | AltName: Full=Gene product E; Short=gpE; |
| Gene name | Name=E; |
| end case | |
Comments
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| case <OC:Lambdavirus> | |
| FUNCTION | Assembles to form an icosahedral capsid with a T=7 symmetry. The icosahedral capsid is about 60 nm in diameter and composed of 415 major capsid proteins. The assembly is primed by the interaction between capsid assembly protease and portal dodecamer, and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein. Major capsid protein forms hexons and pentons of the icosahedron. Viral genomic DNA is packaged into the procapsid through the portal vertex. The packaging triggers a dramatic reconfiguration of the capsid shell. |
| else | |
| FUNCTION | Assembles to form an icosahedral capsid. The assembly is primed by the interaction between capsid assembly protease and portal dodecamer, and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein. Major capsid protein forms hexons and pentons of the icosahedron. Viral genomic DNA is packaged into the procapsid through the portal vertex. The packaging triggers a dramatic reconfiguration of the capsid shell. |
| end case | |
| SUBUNIT | Homomultimer. |
| SUBCELLULAR LOCATION | Virion. Host cytoplasm. Note=Forms the capsid icosahedric shell. |
| SIMILARITY | Belongs to the lambda phage major capsid protein family. |
Keywords
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| Capsid protein | |
| Host cytoplasm | |
| Late protein | |
| case <OC:Lambdavirus> | |
| T=7 icosahedral capsid protein | |
| end case | |
| Virion | |
Gene Ontology
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| GO:0019028; Cellular component:viral capsid |
Cross-references
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| Pfam | PF03864; Phage_cap_E; 1; |
| General | Coiled_coil; -; 0-unlimited; |
Features
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Additional information
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| Size range | 330-370 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |