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HAMAP rule MF_04133

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General rule information [?]

Accession MF_04133
Dates 11-JAN-2019 (Created)
23-AUG-2022 (Last updated, Version 4)
Name CAPSID_LAMBDA
Scope
Viruses; Caudoviricetes
Template P03713 (CAPSD_LAMBD)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CAPSD
Protein name
RecName: Full=Major capsid protein;
AltName: Full=Major head protein;
case <OC:Lambdavirus>
Protein name
AltName: Full=Gene product E;
Short=gpE;
Gene name
E
end case

Comments [?]

case <OC:Lambdavirus>
Function Assembles to form an icosahedral capsid with a T=7 symmetry. The icosahedral capsid is about 60 nm in diameter and composed of 415 major capsid proteins. The assembly is primed by the interaction between capsid assembly protease and portal dodecamer, and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein. Major capsid protein forms hexons and pentons of the icosahedron. Viral genomic DNA is packaged into the procapsid through the portal vertex. The packaging triggers a dramatic reconfiguration of the capsid shell.
else
Function Assembles to form an icosahedral capsid. The assembly is primed by the interaction between capsid assembly protease and portal dodecamer, and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein. Major capsid protein forms hexons and pentons of the icosahedron. Viral genomic DNA is packaged into the procapsid through the portal vertex. The packaging triggers a dramatic reconfiguration of the capsid shell.
end case
Subunit Homomultimer.
Subcellular location Virion. Host cytoplasm. Note=Forms the capsid icosahedric shell.
Similarity Belongs to the lambda phage major capsid protein family.

Keywords [?]

case <OC:Lambdavirus>
end case

Gene Ontology [?]

GO:0019028; Cellular component: viral capsid.

Cross-references [?]

Pfam PF03864; Phage_cap_E; 1;

Computed features [?]

General Coiled_coil; -; 0-unlimited; trigger=yes;

Additional information [?]

Size range 330-370 amino acids
Related rules None
Fusion None