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HAMAP rule MF_04135

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General rule information [?]

Accession MF_04135
Dates 11-JAN-2019 (Created)
1-JUN-2023 (Last updated, Version 7)
Scope(s) Viruses
Template(s) P03710 (PORTL_LAMBD); [ Recover all ]
Triggered by HAMAP; MF_04135 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PORTL
case <OC:Lambdavirus>
Protein name RecName: Full=Portal protein B;
AltName: Full=GpB;
AltName: Full=Minor capsid protein B;
Protein name RecName: Full=Portal protein;
end case
case <FTTag:cleavage>
Protein name Contains:
RecName: Full=Protein B*;
end case
case <OC:Lambdavirus>
Gene name Name=B;
end case

Comments [?]

FUNCTIONForms the portal vertex of the capsid. This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel. Binds to the terminase subunits to form the packaging machine.
SUBUNITHomododecamer. Interacts with the terminase complex composed of two small and one large terminase subunits.
PTMProteolytically cleaved by the viral protease during capsid maturation.
SIMILARITYBelongs to the siphoviridae portal protein family.

Keywords [?]

Gene Ontology [?]

GO:0046798; Cellular component:viral portal complex
GO:0005198; Molecular function:structural molecule activity
case <OCellular component:Lambdavirus>
GO:0099001; Biological process:viral genome ejection through host cell envelope, long flexible tail mechanism
end case
GO:0019068; Biological process:virion assembly

Cross-references [?]

Pfam PF05136; Phage_portal_2; 1;
NCBIfam TIGR01539; portal_lambda; 1;
General Coiled_coil; -; 0-unlimited;

Features [?]

From: PORTL_LAMBD (P03710)
Key From To Description Tag Condition FTGroup
case <OC:Lambdavirus>
CHAIN Nter Cter /note="Portal protein B"
CHAIN Nter Cter /note="Portal protein"
end case
SITE 22 23 /note="Cleavage; by viral protease" cleavage [GA]-G
case <FTTag:cleavage>
CHAIN 23 Cter /note="Protein B*"
end case

Additional information [?]

Size range 490-590 amino acids
Related rules None
Fusion Nter: None Cter: None

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