HAMAP rule MF_04159

General rule information [?]

Accession	MF_04159
Dates	6-APR-2021 (Created) 20-APR-2021 (Last updated, Version 2)
Name	SPACKLE_T4
Scope(s)	Viruses
Template(s)	P39230 (SPAC_BPT4); [ Recover all ]
Triggered by	HAMAP; MF_04159 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	SPAC
Protein name	RecName: Full=Protein spackle;
case <Feature:Signal>
Protein name	+ Flags: Precursor;
end case
case <OC:Tequatrovirus>
Gene name	Name=sp; Synonyms=61.3;
end case

Comments [?]

FUNCTION	Inhibits viral DNA ejection into the host cytoplasm, thereby confering the infected host bacteria with immunity against secondary phage infection. Achieves superinfection exclusion by localizing to the periplasm and inhibiting the activity of tail-associated lysozyme, thereby preventing penetration by the tail tube of incoming phages.
case <OS:Enterobacteria phage T4>
SUBUNIT	Monomer. Interacts with the baseplate central spike protein Gp5; this interaction selectively inhibits the lysozyme activity of the baseplate central spike protein.
else
SUBUNIT	Monomer. Interacts with the baseplate central spike protein; this interaction selectively inhibits the lysozyme activity of the baseplate central spike protein.
end case
SUBCELLULAR LOCATION	Host periplasm.
SIMILARITY	Belongs to the Tevenvirinae spackle protein family.

Keywords [?]

Gene Ontology [?]

GO:0098669; Biological process:superinfection exclusion

Cross-references [?]

General	Signal; -; 0-1;
General	Transmembrane; -; 0-2;

Features [?]

From: SPAC_BPT4 (P39230)

Key

From

Description

Tag

Condition

FTGroup

DISULFID

disulf

C-x*-C

Additional information [?]