HAMAP rule MF_04164

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_04164
Accession	MF_04164
Dates	16-APR-2021 (Created) 20-APR-2021 (Last updated, Version 3)
Name	T4_Sigma-like factor
Scope(s)	Viruses
Template(s)	P04524; [ Recover all ]
Triggered by	HAMAP; MF_04164 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	SIGML
Protein name	RecName: Full=RNA polymerase sigma-like factor; AltName: Full=Promoter specificity factor;

Comments [?]

FUNCTION	Plays a role in the transcription of the viral late genes by acting as a late promoter recognition subunit. Associates with host RNA polymerase (RNAP) core and thus replaces the host sigma-70/rpoD subunit in the complex. May also play a role in DNA packaging by interacting with the terminase subunit gp17.
SUBUNIT	Interacts with the host RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ to form the RNAP-gp55 holoenzyme. Part of the transcription activation complex containing host RNAP, the viral RNA polymerase sigma-like factor, the late transcription coactivator, and the sliding clamp. Interacts with the terminase large subunit; this interaction may load the terminase onto DNA for packaging.
SIMILARITY	Belongs to the Tevenvirinae RNA polymerase sigma-like factor family.

Keywords [?]

Gene Ontology [?]

GO:0016987; Molecular function:sigma factor activity

GO:0003677; Molecular function:DNA binding

GO:0019086; Biological process:late viral transcription