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Annotation rule MF_04165
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General rule information [?]

Accession MF_04165
Dates 16-APR-2021 (Created)
27-APR-2021 (Last updated, Version 3)
Name T4_TRANSCR_COACT
Scope
Viruses
Template P13338 (LTACT_BPT4)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
LTACT
Protein name
RecName: Full=Late transcription coactivator;
AltName: Full=RNA polymerase-associated protein Gp33;

Comments [?]

Function Activates transcription at late promoters when the sliding clamp is present. Binds to both the host RNA polymerase (RNAP) and the upstream dsDNA.
Subunit Interacts with the beta subunit of host RNAP RpoB (via flap domain). Part of the transcription activation complex containing host RNAP, the viral RNA polymerase sigma-like factor, the coactivator gp33, and the sliding clamp.
Domain The C-terminus is involved in transcriptional enhancement.
Similarity Belongs to the Tevenvirinae late transcription coactivator family.

Gene Ontology [?]

GO:0140537; Molecular function: transcription regulator activator activity.
GO:0019086; Biological process: late viral transcription.

Cross-references [?]

Pfam PF16805; Trans_coact; 1;

Features [?]

From: LTACT_BPT4 (P13338)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     62     92       Interaction with host RNAP        
REGION     106     112       Involved in transcriptional enhancement     [NQS]-[NST]-L-[DE]-[DFGI]-[FL]-x  

Additional information [?]

Size range 60-300 amino acids
Related rules None
Fusion None


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