HAMAP rule MF_00028
General rule information
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Accession | MF_00028 |
Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 29) |
Name | CobQ |
Scope(s) |
Bacteria Archaea |
Template(s) | P29932 (COBQ_SINSX); [ Recover all ] |
Triggered by |
HAMAP; MF_00028 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | COBQ |
case <OC:Bacteria> | |
Protein name | RecName: Full=Cobyric acid synthase; |
end case | |
case <OC:Archaea> | |
Protein name | RecName: Full=Probable cobyric acid synthase; |
end case | |
Gene name | Name=cobQ; |
Comments
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FUNCTION | Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. |
PATHWAY | Cofactor biosynthesis; adenosylcobalamin biosynthesis. |
SIMILARITY | Belongs to the CobB/CobQ family. CobQ subfamily. |
Keywords
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Gene Ontology
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GO:0015420; Molecular function:ABC-type vitamin B12 transporter activity |
Cross-references
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Pfam | PF01656; CbiA; 1; |
Pfam | PF07685; GATase_3; 1; |
NCBIfam | TIGR00313; CobQ; 1; |
PROSITE | PS51274; GATASE_COBBQ; 1; |
Features
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From: COBQ_SINSX (P29932) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 333 | 333 | /note="Nucleophile" | C | ||||||||
ACT_SITE | 430 | 430 | H |
Additional information
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Size range | 464-543 amino acids |
Related rules |
MF_00027 |
Fusion | Nter: None Cter: None |
Comments | Called cbiP in Salmonella |