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HAMAP rule MF_00106

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General rule information [?]

Accession MF_00106
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 30)
Name UxuA
Scope(s) Bacteria
Template(s) P24215 (UXUA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00106 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier UXUA
Protein name RecName: Full=Mannonate dehydratase;
                 EC=4.2.1.8;
AltName: Full=D-mannonate hydro-lyase;
Gene name Name=uxuA;

Comments [?]

FUNCTIONCatalyzes the dehydration of D-mannonate.
CATALYTIC ACTIVITY Reaction=D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O; Xref=Rhea:RHEA:20097, ChEBI:CHEBI:15377, ChEBI:CHEBI:17767, ChEBI:CHEBI:57990; EC=4.2.1.8;
COFACTOR Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
PATHWAYCarbohydrate metabolism; pentose and glucuronate interconversion.
SIMILARITYBelongs to the mannonate dehydratase family.

Keywords [?]


Gene Ontology [?]

GO:0008927; Molecular function:mannonate dehydratase activity

Cross-references [?]

Pfam PF03786; UxuA; 1;
NCBIfam TIGR00695; UxuA; 1;

Features [?]


Additional information [?]

Size range 345-402 amino acids
Related rules None
Fusion Nter: None Cter: None



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