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HAMAP rule MF_00129

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General rule information [?]

Accession MF_00129
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 37)
Name MnmG_GidA
Scope(s) Bacteria
Template(s) P0A6U3 (MNMG_ECOLI); O66962 (MNMG_AQUAE); Q8KA85 (MNMG_CHLTE); [ Recover all ]
Triggered by HAMAP; MF_00129 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MNMG
Protein name RecName: Full=tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG;
AltName: Full=Glucose-inhibited division protein A;
Gene name Name=mnmG; Synonyms=gidA;

Comments [?]

FUNCTIONNAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
COFACTOR Name=FAD; Xref=ChEBI:CHEBI:57692;
SUBUNITHomodimer. Heterotetramer of two MnmE and two MnmG subunits.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the MnmG family.

Keywords [?]


Gene Ontology [?]

GO:0050660; Molecular function:flavin adenine dinucleotide binding
GO:0008033; Biological process:tRNA processing
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01134; GIDA; 1;
NCBIfam TIGR00136; GidA; 1;
PROSITE PS01280; GIDA_1; 1;
PROSITE PS01281; GIDA_2; 1;

Features [?]

From: MNMG_ECOLI (P0A6U3)
Key From To Description Tag Condition FTGroup
BINDING 13 18 /ligand="FAD"
/ligand_id="ChEBI:CHEBI:57692"
G-[GATL]-G-H-[AS]-G
BINDING 273 287 /ligand="NAD(+)"
/ligand_id="ChEBI:CHEBI:57540"
[GSA]-x-[RL]-[YH]-C-P-S-[IVFL]-[ED]-x-K-[VIFAL]-x-x-[FY]
BINDING 125 125 /ligand="FAD"
/ligand_id="ChEBI:CHEBI:57692"
[VI] 1
BINDING 180 180 /ligand="FAD"
/ligand_id="ChEBI:CHEBI:57692"
[ST] 1
BINDING 370 370 /ligand="FAD"
/ligand_id="ChEBI:CHEBI:57692"
[QN] 1

Additional information [?]

Size range 500-685 amino acids
Related rules None
Fusion Nter: None Cter: None



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