HAMAP rule MF_00196
General rule information
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| Accession | MF_00196 |
| Dates | 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 24) |
| Name | Mannitol_dehydrog |
| Scope(s) |
Bacteria |
| Template(s) | P09424 (MTLD_ECOLI); P27543 (MTLD_ENTFA); Q02418 (MTLD_STRMU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00196 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MTLD |
| Protein name | RecName: Full=Mannitol-1-phosphate 5-dehydrogenase; EC=1.1.1.17; |
| Gene name | Name=mtlD; |
Comments
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| CATALYTIC ACTIVITY | Reaction=D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH; Xref=Rhea:RHEA:19661, ChEBI:CHEBI:15378, ChEBI:CHEBI:57540, ChEBI:CHEBI:57634, ChEBI:CHEBI:57945, ChEBI:CHEBI:61381; EC=1.1.1.17; |
| SIMILARITY | Belongs to the mannitol dehydrogenase family. |
Keywords
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| case <FT:2> | |
| Acetylation | |
| end case | |
| Oxidoreductase | |
| NAD | |
Gene Ontology
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| GO:0008926; Molecular function:mannitol-1-phosphate 5-dehydrogenase activity |
Cross-references
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| Pfam | PF01232; Mannitol_dh; 1; |
| PRINTS | PR00084; MTLDHDRGNASE; 1; |
| PROSITE | PS00974; MANNITOL_DHGENASE; 1; |
Features
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| From: MTLD_ECOLI (P09424) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 3 | 14 | /ligand="NAD(+)" /ligand_id="ChEBI:CHEBI:57540" |
x(3)-F-G-A-G-N-I-G-R-G | ||||||||
| case <OC:Escherichia> or <OC:Shigella> | ||||||||||||
| MOD_RES | 269 | 269 | /note="N6-acetyllysine" | K | ||||||||
| end case | ||||||||||||
Additional information
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| Size range | 360-388 amino acids |
| Related rules |
MF_00670 |
| Fusion | Nter: None Cter: None |