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HAMAP rule MF_00309

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General rule information [?]

Accession MF_00309
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 35)
Name ATP_synth_A_arch
Scope(s) Bacteria
Archaea
Template(s) Q48332 (VATA_HALVD); [ Recover all ]
Triggered by HAMAP; MF_00309 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier VATA
Protein name RecName: Full=V-type ATP synthase alpha chain;
                 EC=7.1.2.2;
AltName: Full=V-ATPase subunit A;
Gene name Name=atpA;

Comments [?]

case <OC:Archaea>
FUNCTIONProduces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.
end case
case <OC:Bacteria>
FUNCTIONProduces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.
end case
CATALYTIC ACTIVITY Reaction=ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate; Xref=Rhea:RHEA:57720, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.1.2.2;
SIMILARITYBelongs to the ATPase alpha/beta chains family.

Keywords [?]

<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>
ATP synthesis
Nucleotide-binding
Transport
Ion transport
Hydrogen ion transport
ATP-binding

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0046933; Molecular function:proton-transporting ATP synthase activity, rotational mechanism
GO:0042777; Biological process:proton motive force-driven plasma membrane ATP synthesis

Cross-references [?]

Pfam PF00006; ATP-synt_ab; 1;
Pfam PF00306; ATP-synt_ab_C; 1;
NCBIfam TIGR01043; ATP_syn_A_arch; 1;
PROSITE PS00152; ATPASE_ALPHA_BETA; 1;

Features [?]

From: VATA_METJA (Q57670)
Key From To Description Tag Condition FTGroup
BINDING 234 241 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
G-x-F-G-[STA]-G-K-T

Additional information [?]

Size range 570-605 amino acids
Related rules MF_00310
Fusion Nter: None Cter: None
Comments Inteins deleted in PYRAB, PYRHO and THEAC



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