HAMAP rule MF_00492
General rule information
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| Accession | MF_00492 |
| Dates | 28-NOV-2001 (Created)
1-JUN-2023 (Last updated, Version 37) |
| Name | Transaldolase_1 |
| Scope(s) |
Bacteria |
| Template(s) | P0A867 (TALA_ECOLI); P0A870 (TALB_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00492 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | TAL |
| Protein name | RecName: Full=Transaldolase; EC=2.2.1.2; |
| Gene name | Name=tal; |
Comments
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| FUNCTION | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. |
| CATALYTIC ACTIVITY | Reaction=D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate; Xref=Rhea:RHEA:17053, ChEBI:CHEBI:16897, ChEBI:CHEBI:57483, ChEBI:CHEBI:57634, ChEBI:CHEBI:59776; EC=2.2.1.2; |
| PATHWAY | Carbohydrate degradation; pentose phosphate pathway; D- glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D- ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the transaldolase family. Type 1 subfamily. |
Keywords
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Gene Ontology
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| GO:0004801; Molecular function:transaldolase activity |
| GO:0006098; Biological process:pentose-phosphate shunt |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF00923; Transaldolase; 1; |
| PROSITE | PS01054; TRANSALDOLASE_1; 1; |
| PROSITE | PS00958; TRANSALDOLASE_2; 1; |
| NCBIfam | TIGR00874; talAB; 1; |
Features
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| From: TALB_ECOLI (P0A870) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 132 | 132 | /note="Schiff-base intermediate with substrate" | K | ||||||||
Additional information
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| Size range | 307-397 amino acids |
| Related rules |
MF_00493 MF_00494 MF_00496 |
| Fusion | Nter: None Cter: <Unknown> |
| Comments | C-terminal domain that contains 2 EF-hands in GLOVI, PROMM, THEVB, PARMW, SYNY3 |