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HAMAP rule MF_00496

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General rule information [?]

Accession MF_00496
Dates 30-NOV-2001 (Created)
1-JUN-2023 (Last updated, Version 25)
Name F6P_aldolase
Scope(s) Bacteria
Template(s) P78055 (FSAA_ECOLI); P32669 (FSAB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00496 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier FSA
case <OC:Enterobacterales>
Protein name RecName: Full=Fructose-6-phosphate aldolase;
                 EC=4.1.2.-;
else
Protein name RecName: Full=Probable fructose-6-phosphate aldolase;
                 EC=4.1.2.-;
end case
Gene name Name=fsa;

Comments [?]

FUNCTIONCatalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
CATALYTIC ACTIVITY Reaction=beta-D-fructose 6-phosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone; Xref=Rhea:RHEA:28002, ChEBI:CHEBI:16016, ChEBI:CHEBI:57634, ChEBI:CHEBI:59776;
case <OC:Enterobacterales>
SUBUNITHomodecamer.
end case
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the transaldolase family. Type 3A subfamily.

Keywords [?]


Gene Ontology [?]

GO:0016832; Molecular function:aldehyde-lyase activity
GO:0006000; Biological process:fructose metabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00923; Transaldolase; 1;
NCBIfam TIGR00875; fsa_talC_mipB; 1;
PROSITE PS01054; TRANSALDOLASE_1; 1;
PROSITE PS00958; TRANSALDOLASE_2; 1;

Features [?]

From: FSAA_ECOLI (P78055)
Key From To Description Tag Condition FTGroup
ACT_SITE 85 85 /note="Schiff-base intermediate with substrate" K

Additional information [?]

Size range 220-222 amino acids
Related rules MF_00492
MF_00493
MF_00494
Fusion Nter: None Cter: None



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