HAMAP rule MF_00621
General rule information
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| Accession | MF_00621 |
| Dates | 27-FEB-2003 (Created)
1-JUN-2023 (Last updated, Version 29) |
| Name | HTH_type_CodY |
| Scope(s) |
Bacteria |
| Template(s) | P39779 (CODY_BACSU); A2RHP2 (CODY_LACLM); Q81WK7 (CODY_BACAN); Q04JG7 (CODY_STRP2); Q2FZ27 (CODY_STAA8); A7X1N2 (CODY_STAA1); [ Recover all ] |
| Triggered by |
HAMAP; MF_00621 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | CODY |
| Protein name | RecName: Full=Global transcriptional regulator CodY; |
| Gene name | Name=codY; |
Comments
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| FUNCTION | DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the CodY family. |
Keywords
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| Cytoplasm | |
| Transcription | |
| Transcription regulation | |
| Repressor | |
| DNA-binding | |
| case <FTTag:phospho> | |
| Phosphoprotein | |
| end case | |
Gene Ontology
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| GO:0045892; Biological process:negative regulation of DNA-templated transcription |
| GO:0003677; Molecular function:DNA binding |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF06018; CodY; 1; |
| Pfam | PF08222; HTH_CodY; 1; |
| NCBIfam | TIGR02787; CodY_Gpos; 1; |
| PIRSF | PIRSF011572; GTP_sensing_CodY; 1; |
Features
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| From: CODY_BACSU (P39779) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DNA_BIND | 203 | 222 | /note="H-T-H motif" | |||||||||
| REGION | Nter | 155 | /note="GAF domain" | |||||||||
| case <OC:Bacillaceae> | ||||||||||||
| MOD_RES | 215 | 215 | /note="Phosphoserine" | phospho | S | |||||||
| end case | ||||||||||||
Additional information
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| Size range | 220-300 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |